Ferritin in cultured fibroblasts from patients with idiopathic hemochromatosis.

Cultured skin fibroblasts from three unrelated patients with idiopathic hemochromatosis and two normal controls were cultured in media containing iron concentrations ranging from 383 to 963 ng/ml. The amount of ferritin accumulating in fibroblasts was related to the iron concentrations, but there was no significant difference in the fibroblasts of patients with hemochromatosis and the normal controls.