Texture of white blood cells expressed by the counting densitogram.

The counting of particles and holes in white blood cells during thresholding at different gray levels results in a histogram, the counting densitogram, which contains information about granularity. Parameters describing the shape of this histogram appear to be sufficiently characteristic for the five normal white blood cell classes to allow a 84% correct discrimination between them. This method to quantitate granularity could be valuable for the analysis of cell texture and therefore, when used in combination with geometrical and density histogram parameters, could contribute to the results of morphometric discrimination between other than normal white blood cells.