Literature DB >> 7273276

Styrene and styrene oxide induce SCEs and are metabolised in human lymphocyte cultures.

H Norppa, M Sorsa, P Pfäffli, H Vainio.   

Abstract

Both styrene and its presumed active metabolite styrene oxide show dose response as potent inducers of sister chromatid exchanges (SCEs) in human lymphocyte cultures. The SCE inducing and clastogenic capacity of styrene in lymphocytes in vitro can be explained by gas chromatographically measurable increase of styrene oxide in styrene treated cultures.

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Year:  1980        PMID： 7273276     DOI： 10.1093/carcin/1.4.357

Source DB:  PubMed          Journal:  Carcinogenesis        ISSN： 0143-3334            Impact factor:   4.944


  5 in total

1.  Determination of low level exposure to volatile aromatic hydrocarbons and genotoxic effects in workers at a styrene plant.

Authors:  O Holz; G Scherer; S Brodtmeier; F Koops; K Warncke; T Krause; A Austen; J Angerer; A R Tricker; F Adlkofer
Journal:  Occup Environ Med       Date:  1995-06       Impact factor: 4.402

2.  Intervention study on the influence of reduction of occupational exposure to styrene on sister chromatid exchanges in lymphocytes.

Authors:  E Hallier; H W Goergens; K Hallier; H M Bolt
Journal:  Int Arch Occup Environ Health       Date:  1994       Impact factor: 3.015

3.  Monitoring of exposure to styrene oxide by GC-MS analysis of phenylhydroxyethyl esters in hemoglobin.

Authors:  O Sepai; D Anderson; B Street; I Bird; P B Farmer; E Bailey
Journal:  Arch Toxicol       Date:  1993       Impact factor: 5.153

4.  Evaluation of low exposure to styrene. I. Absorption of styrene vapours by inhalation under experimental conditions.

Authors:  H Wieczorek; J K Piotrowski
Journal:  Int Arch Occup Environ Health       Date:  1985       Impact factor: 3.015

5.  Acetaldehyde and hexanaldehyde from cultured white cells.

Authors:  Hye-Won Shin; Brandon J Umber; Simone Meinardi; Szu-Yun Leu; Frank Zaldivar; Donald R Blake; Dan M Cooper
Journal:  J Transl Med       Date:  2009-04-29       Impact factor: 5.531
  5 in total

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