Literature DB >> 7272845

Failure to detect soluble tumor associated antigen by radioimmunoassay in bovine lymphoma.

R M Jacobs, V E Valli, B N Wilkie.   

Abstract

The detection of circulating soluble tumor-associated antigen by radioimmunoassay was attempted in cows with lymphoma. The assay system did detect PAGE-purified tumor-associated antigen but did not detect immunoreactive substances in the sera of 20 affected animals and 20 normal cattle. Similarly, ultrafiltration of low pH-dissociated serum to separate immune complexes did not aid in the detection of antigen.

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Year:  1981        PMID： 7272845      PMCID： PMC1320125     

Source DB:  PubMed          Journal:  Can J Comp Med        ISSN： 0008-4050


  29 in total

Review 1.  Avian RNA tumor viruses. A model for studying tumor associated cell surface alterations.

Authors:  R Kurth; H Bauer
Journal:  Biochim Biophys Acta       Date:  1975-03-20

2.  Influence of culture conditions of growth of FL-74 cells and feline oncornavirus cell membrane associated antigen production.

Authors:  R G Olsen; G E Milo; J P Schaller; L E Mathes; L Heding; D S Yohn
Journal:  In Vitro       Date:  1976-01

3.  Comparison of direct and indirect solid-phase microradioimmunoassays for the detection of viral antigens and antiviral antibody.

Authors:  J D Rosenthal; K Hayashi; A L Notkins
Journal:  Appl Microbiol       Date:  1973-04

4.  Blocking of lymphocyte-mediated cytotoxicity for rat hepatoma cells by tumour-specific antigen-antibody complexes.

Authors:  R W Baldwin; M R Price; R A Robins
Journal:  Nat New Biol       Date:  1972-08-09

5.  Serum factors in tumor-free patients cancelling the blocking of cell-mediated tumor immunity.

Authors:  I Hellström; K E Hellström; H O Sjögren; G A Warner
Journal:  Int J Cancer       Date:  1971-09-15       Impact factor: 7.396

6.  Blocking of cell-mediated tumor immunity by sera from patients with growing neoplasms.

Authors:  I Hellström; H O Sjögren; G Warner; K E Hellström
Journal:  Int J Cancer       Date:  1971-03-15       Impact factor: 7.396

7.  Soluble tumour-specific antigen and its relationship to tumour growth.

Authors:  D M Thomson
Journal:  Int J Cancer       Date:  1975-06-15       Impact factor: 7.396

8.  Suggestive evidence that the "blocking antibodies" of tumor-bearing individuals may be antigen--antibody complexes.

Authors:  H O Sjögren; I Hellström; S C Bansal; K E Hellström
Journal:  Proc Natl Acad Sci U S A       Date:  1971-06       Impact factor: 11.205

9.  Serum mediated inhibition of the immunological reactions of the patient to his own tumour: a possible role for circulating antigen.

Authors:  G A Currie; C Basham
Journal:  Br J Cancer       Date:  1972-12       Impact factor: 7.640

10.  The presence of tumour-specific membrane antigen in the serum of rats with chemically induced sarcomata.

Authors:  D M Thomson; K Steele; P Alexander
Journal:  Br J Cancer       Date:  1973-01       Impact factor: 7.640
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