Literature DB >> 7272197

An objective assessment of the tube spacer in patients unable to use a conventional pressurized aerosol efficiently.

D J Godden, G K Crompton.   

Abstract

The tube spacer, a device designed to simplify the inhalation of terbutaline from a pressurized aerosol, was objectively assessed in a group of patients with reversible airways obstruction who were found to have some difficulty in using conventional inhalers. Terbutaline was administered to 22 patients in a dose of 250 micrograms via the conventional pressurized aerosol and the tube spacer. In 16 the improvements in FEV1 were greater after the tube spacer, in four they were greater after the conventional inhaler and in two patients there was no difference. Using an open sequential plan for evaluation of paired preferences it was concluded that the tube spacer was better than the conventional inhaler in these patients.

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Year:  1981        PMID: 7272197     DOI: 10.1016/0007-0971(81)90049-8

Source DB:  PubMed          Journal:  Br J Dis Chest        ISSN: 0007-0971


  11 in total

1.  Comparison of two chamber devices in patients using a metered-dose inhaler with satisfactory technique.

Authors:  H D Fuller
Journal:  CMAJ       Date:  1986-09-15       Impact factor: 8.262

Review 2.  New drugs in respiratory disorders: I.

Authors:  D C Flenley
Journal:  Br Med J (Clin Res Ed)       Date:  1983-03-12

Review 3.  A more logical approach to asthma.

Authors:  M R Hetzel
Journal:  Postgrad Med J       Date:  1984-03       Impact factor: 2.401

4.  Terbutaline aerosol given through pear spacer in acute severe asthma.

Authors:  M D Morgan; B V Singh; M H Frame; S J Williams
Journal:  Br Med J (Clin Res Ed)       Date:  1982-09-25

Review 5.  Spacer devices for metered dose inhalers.

Authors:  Stephen P Newman
Journal:  Clin Pharmacokinet       Date:  2004       Impact factor: 6.447

Review 6.  Pharmacokinetic optimisation of inhaled steroid therapy in asthma.

Authors:  I Pavord; A Knox
Journal:  Clin Pharmacokinet       Date:  1993-08       Impact factor: 6.447

7.  High-dose inhaled terbutaline in the management of chronic severe asthma: comparison of wet nebulisation and tube-spacer delivery.

Authors:  J G Prior; R V Nowell; G M Cochrane
Journal:  Thorax       Date:  1982-04       Impact factor: 9.139

Review 8.  Chronic obstructive pulmonary disease.

Authors:  N R Anthonisen
Journal:  CMAJ       Date:  1988-03-15       Impact factor: 8.262

Review 9.  Inhalation devices for asthma. Choosing the right one could make all the difference.

Authors:  P M Fong; D E Sinclair
Journal:  Can Fam Physician       Date:  1993-11       Impact factor: 3.275

10.  Acute dose-response studies in bronchial asthma with a new corticosteroid, budesonide.

Authors:  R Ellul-Micallef; S A Johansson
Journal:  Br J Clin Pharmacol       Date:  1983-04       Impact factor: 4.335

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