Literature DB >> 7264927

Studies on drug metabolism by use of isotopes XXVI: Determination of urinary metabolites of rutin in humans.

S Baba, T Furuta, M Horie, H Nakagawa.   

Abstract

Determination of urinary metabolites of orally administered rutin and rutin-2',5',6'-d3 in humans was carried out by TLC and GLC-mass spectrometry. In human urine, 3-hydroxyphenylacetic acid, 3-methoxy-4-hydroxyphenylacetic acid, 3,4-dihydroxyphenylacetic acid, 3,4-dihydroxytoluene, and beta-m-hydroxyphenylhydracrylic acid were identified as rutin metabolites. Unchanged rutin and quercetin were not present in urine.

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Year:  1981        PMID： 7264927     DOI： 10.1002/jps.2600700717

Source DB:  PubMed          Journal:  J Pharm Sci        ISSN： 0022-3549            Impact factor:   3.534


  3 in total

Review 1.  The phenolic interactome and gut microbiota: opportunities and challenges in developing applications for schizophrenia and autism.

Authors:  George E Jaskiw; Mark E Obrenovich; Curtis J Donskey
Journal:  Psychopharmacology (Berl)       Date:  2019-06-13       Impact factor: 4.530

Review 2.  Mechanisms Underlying the Antidiabetic Activities of Polyphenolic Compounds: A Review.

Authors:  Tina Nie; Garth J S Cooper
Journal:  Front Pharmacol       Date:  2021-12-14       Impact factor: 5.810

3.  Inhibitory effect of catecholic colonic metabolites of rutin on fatty acid hydroperoxide and hemoglobin dependent lipid peroxidation in Caco-2 cells.

Authors:  Agustin Martin Morales; Rie Mukai; Kaeko Murota; Junji Terao
Journal:  J Clin Biochem Nutr       Date:  2018-07-12       Impact factor: 3.114
  3 in total

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