Literature DB >> 7264285

Stressful life events and the return to heroin use.

D W Krueger.   

Abstract

Patients on methadone maintenance were studied to determine which factors influence the continuation of heroin-free treatment, as opposed to the return to drug abuse. Psychosocial data, a Zung Depression Scale, and the Social Readjustment Rating Scale (SRRS) were collected on those patients who returned to heroin use while on a methadone maintenance program during the one year of study (n = 48); they were compared to a control group as well as to themselves during a heroin-free maintenance period. The group of patients returning to heroin use showed the existence of such events as recent loss, depression, and exacerbation of intense affect coinciding with the occurrence of heroin use. Furthermore, their SRRS scores and number of SRRS items were significantly higher than those of the control group and than their own steady-state scores. The number and magnitude of stressful life events seem significantly related to patients' not adhering to methadone maintenance and returning to heroin use. The understanding of the importance and adaptive function of drugs to the addict in regulating and ameliorating otherwise overwhelming and catastrophic affective states is underscored otherwise overwhelming and catastrophic affective states is underscored by this study. The total number of life stress events as well as the specificity of meaning to the patient are both emotionally important in understanding, intervening, and treating these patients.

Entities:  

Mesh:

Substances:

Year:  1981        PMID: 7264285     DOI: 10.1080/0097840X.1981.9936820

Source DB:  PubMed          Journal:  J Human Stress        ISSN: 0097-840X


  8 in total

1.  Enhanced dendritic availability of μ-opioid receptors in inhibitory neurons of the extended amygdala in mice deficient in the corticotropin-releasing factor-1 receptor.

Authors:  Azra Jaferi; Ping Zhou; Virginia M Pickel
Journal:  Synapse       Date:  2011-01       Impact factor: 2.562

2.  Stress reinstates heroin-seeking in drug-free animals: an effect mimicking heroin, not withdrawal.

Authors:  Y Shaham; J Stewart
Journal:  Psychopharmacology (Berl)       Date:  1995-06       Impact factor: 4.530

3.  Experiencing violence as a predictor of drug use relapse among former drug users in Baltimore, Maryland.

Authors:  Cui Yang; Danielle German; Daniel Webster; Carl Latkin
Journal:  J Urban Health       Date:  2011-12       Impact factor: 3.671

4.  Perceptions of partners' problematic alcohol use affect relationship outcomes beyond partner self-reported drinking: alcohol use in committed romantic relationships.

Authors:  Lindsey M Rodriguez; Camilla S Øverup; Camilla S Overup; Clayton Neighbors
Journal:  Psychol Addict Behav       Date:  2013-02-25

5.  Imagery scripts and a computerized subtraction stress task both induce stress in methamphetamine users: a controlled laboratory study.

Authors:  Kathleen J Garrison; Jeremy R Coyle; Matthew J Baggott; John Mendelson; Gantt P Galloway
Journal:  Subst Abuse       Date:  2010-10-26

Review 6.  Elevated Norepinephrine may be a Unifying Etiological Factor in the Abuse of a Broad Range of Substances: Alcohol, Nicotine, Marijuana, Heroin, Cocaine, and Caffeine.

Authors:  Paul J Fitzgerald
Journal:  Subst Abuse       Date:  2013-10-13

7.  Does Prison Crowding Predict Higher Rates of Substance Use Related Parole Violations? A Recurrent Events Multi-Level Survival Analysis.

Authors:  Michael A Ruderman; Deirdra F Wilson; Savanna Reid
Journal:  PLoS One       Date:  2015-10-22       Impact factor: 3.240

Review 8.  Social defeat stress and escalation of cocaine and alcohol consumption: Focus on CRF.

Authors:  Emily L Newman; Michael Z Leonard; Danielle T Arena; Rosa M M de Almeida; Klaus A Miczek
Journal:  Neurobiol Stress       Date:  2018-09-19
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.