| Literature DB >> 7263821 |
Abstract
A normal-phase high-performance liquid chromatographic method was developed to determine the concentration of timethoprim, sulfadiazine and its N4-acetyl derivative in human serum and urine. The unchanged compounds and the metabolite are extracted in organic solvent by a single extraction. The method is accurate and sensitive and suited for pharmacokinetic studies in man.Entities:
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Year: 1981 PMID： 7263821 DOI： 10.1016/s0378-4347(00)80138-3
Source DB: PubMed Journal: J Chromatogr