Exponential model for a two-ligand, regulatory enzyme. Part 2: Performance tests of the 'INDEXP' computer program for the determination of model constants from initial velocity data. I. Artificial data.

The exponential model for a regulatory enzyme describes the relationship between the initial velocity of the catalysed reaction and the concentration of two ligands. A program, entitled 'INDEXP' has been designed to analyse rate data in terms of the model (Kinderlerer et at., 1981) and, in this report, its performance is examined when presented with artificial data generated from known constants and random, normally distributed error. It is shown that 'INDEXP' is able to recover good estimates of the constants.