Biomicroscopic and histologic pathology of the eye in riboflavin deficient rainbow trout (Salmogairdneri).

Quadruplicate lots of 35 fingerling rainbow trout (mean body weight 11.2 g) were fed for 20 weeks a complete diet or one deficient in riboflavin. Five fish from each low were examined for ocular lesions each week. At the end of the experiment eyes of three fish form each lot were examined histologically. Beginning with the 14th week, epithelial changes were present in the cornea; they appeared as thickening of the stroma and endothelium and resulted in clouding. Opacity of the lens originated in the posterior subcapsular cortex and progressed to lens fiber autolysis and liquefaction.