Literature DB >> 7260832

Father-son testicular malignancy. Does genetic anticipation occur?

D Raghavan, T Jelihovsky, R M Fox.   

Abstract

Testicular malignancy in a father and son is reported. The father had sequential bilateral seminomas while the son had embryonal cell carcinoma and seminoma. Reported cases of father-son testicular malignancy are reviewed and a predominance of seminomas in the fathers is apparent while the sons' tumors are highly malignant teratomas, choriocarcinomas and embryonal cell carcinomas. The possibility of genetic anticipation in father-son testicular malignancy is discussed.

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Year:  1980        PMID: 7260832     DOI: 10.1002/1097-0142(19800301)45:5<1005::aid-cncr2820450529>3.0.co;2-0

Source DB:  PubMed          Journal:  Cancer        ISSN: 0008-543X            Impact factor:   6.860


  3 in total

1.  Birth dates of men with cancer of the testis.

Authors:  E G Knox; C Cummins
Journal:  J Epidemiol Community Health       Date:  1985-09       Impact factor: 3.710

2.  Familial testicular cancer: a report of the UK family register, estimation of risk and an HLA class 1 sib-pair analysis.

Authors:  D Forman; R T Oliver; A R Brett; S G Marsh; J H Moses; J G Bodmer; C E Chilvers; M C Pike
Journal:  Br J Cancer       Date:  1992-02       Impact factor: 7.640

3.  Familial testicular cancer in Norway and southern Sweden.

Authors:  K Heimdal; H Olsson; S Tretli; P Flodgren; A L Børresen; S D Fossa
Journal:  Br J Cancer       Date:  1996-04       Impact factor: 7.640

  3 in total

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