Literature DB >> 726081

A second study of the use of community leaders in case-finding for pulmonary tuberculosis in Kenya.

J A Aluoch, W K Karuga, H Nsanzumuhire, E A Edwards, H Stott, W Fox, I Sutherland.   

Abstract

This is the second study of case-finding activities for tuberculosis suspects undertaken in 2 locations of Machakos District. Three methods were investigated, namely (1) the requestioning of the Community Elders 1 year or more after a first questioning in the original study, (2) the examination of patients registered in the District Tuberculosis Register from 1969--1974 and (3) the examination of their close contacts. Requestioning the Elders produced a total of 421 suspects, 129 (31%) of whom had not been identified a year previously. The yield of freshly identified smear-positive, culture-positive cases was 0.7 per 100 suspects examined and of all culture-positive cases was 1.7. However, all the smear-positive and 1.0 per 100 of the culture-positive cases were old patients who had previously been registered in the District Tuberculosis Register. Of the 181 patients with tuberculosis in the Register bacteriological results were available for 97; of these 6 were smear-positive, 9 culture-positive--yields of 6.2 smear-positive, culture-positive cases per 100 registered persons examined. The corresponding yields for the 63 persons who had been registered as having pulmonary disease were 9.5 and 14.3. Of the 9 culture-positive, 7 had strains resistant to isoniazid, but all were sensitive to streptomycin. The examination of the 628 close contacts of the registered patients produced only 3 culture-positive cases, none of whom was smear-positive--a yield of 0.5 culture-positive cases per 100 contacts examined. All 3 strains were sensitive to isoniazid and streptomycin.

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Year:  1978        PMID: 726081     DOI: 10.1016/0041-3879(78)90001-6

Source DB:  PubMed          Journal:  Tubercle        ISSN: 0041-3879


  4 in total

Review 1.  Active case finding of tuberculosis: historical perspective and future prospects.

Authors:  J E Golub; C I Mohan; G W Comstock; R E Chaisson
Journal:  Int J Tuberc Lung Dis       Date:  2005-11       Impact factor: 2.373

2.  Contact investigation in households of patients with tuberculosis in Hanoi, Vietnam: a prospective cohort study.

Authors:  Gregory James Fox; Nguyen Viet Nhung; Dinh Ngoc Sy; Luu Thi Lien; Nguyen Kim Cuong; Warwick John Britton; Guy Barrington Marks
Journal:  PLoS One       Date:  2012-11-15       Impact factor: 3.240

Review 3.  Contact investigation for tuberculosis: a systematic review and meta-analysis.

Authors:  Gregory J Fox; Simone E Barry; Warwick J Britton; Guy B Marks
Journal:  Eur Respir J       Date:  2012-08-30       Impact factor: 16.671

4.  Prevalence of tuberculosis, HIV and respiratory symptoms in two Zambian communities: implications for tuberculosis control in the era of HIV.

Authors:  Helen Ayles; Albertus Schaap; Amos Nota; Charalambos Sismanidis; Ruth Tembwe; Petra De Haas; Monde Muyoyeta; Nulda Beyers
Journal:  PLoS One       Date:  2009-05-19       Impact factor: 3.240

  4 in total

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