Literature DB >> 7260547

Urinary protein profiles in patients with urothelial bladder tumours.

L Hemmingsen, F Rasmussen, P Skaarup, H Wolf.   

Abstract

Urinary protein profiles were studied in 32 patients with urothelial bladder tumours, using immunonephelometry. In patients without residual or recurrent tumours a glomerular type of proteinuria was demonstrated. In patients with grade III-IV transitional cell carcinoma the glomerular proteinuria was more severe than in patients with grade I-II tumours. Increased excretion of low molecular weight proteins was observed only in patients with grade III-IV tumours. The use of the increased relative clearance of albumin, transferrin, and haptoglobin as a diagnostic test was attempted in detecting residual or recurrent tumours. In patients with grade III-IV tumours the predictive value of a positive or negative test was 92% and 100% respectively, whereas the relative protein clearance was without predictive value in patients with grade I-II tumours.

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Year:  1981        PMID： 7260547     DOI： 10.1111/j.1464-410x.1981.tb03189.x

Source DB:  PubMed          Journal:  Br J Urol        ISSN： 0007-1331


  5 in total

1.  Development of a novel proteomic approach for the detection of transitional cell carcinoma of the bladder in urine.

Authors:  A Vlahou; P F Schellhammer; S Mendrinos; K Patel; F I Kondylis; L Gong; S Nasim; G L Wright
Journal:  Am J Pathol       Date:  2001-04       Impact factor: 4.307

2.  Transferrin receptor expression by human bladder transitional cell carcinomas.

Authors:  G J Seymour; M D Walsh; M F Lavin; G Strutton; R A Gardiner
Journal:  Urol Res       Date:  1987

3.  Identification of genes up-regulated in urothelial tumors: the 67-kd laminin receptor and tumor-associated trypsin inhibitor.

Authors:  Christine P Diggle; Sheena Cruickshank; Jonathon D Olsburgh; Stephanie Pellegrin; Barbara Smith; Rosamonde E Banks; Peter J Selby; Margaret A Knowles; Jennifer Southgate; Patricia Harnden
Journal:  Am J Pathol       Date:  2003-08       Impact factor: 4.307

4.  Urinary concentrations of the soluble adhesion molecule E-cadherin and total protein in patients with bladder cancer.

Authors:  A S Protheroe; R E Banks; M Mzimba; W H Porter; J Southgate; P N Singh; M Bosomworth; P Harnden; P H Smith; P Whelan; P J Selby
Journal:  Br J Cancer       Date:  1999-04       Impact factor: 7.640

5.  A case with significant proteinuria caused by secreted protein from urothelial carcinoma.

Authors:  Masanori Sakakima; Yoshihide Fujigaki; Hideo Yasuda; Akashi Togawa; Tomoyuki Fujikura; Atsushi Otsuka; Seiichiro Ozono; Akira Hishida
Journal:  Case Rep Nephrol       Date:  2011-12-15
  5 in total

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