Literature DB >> 7260405

Flexibility of erythrocytes in juvenile diabetes mellitus.

W Tillmann, A Merten, M Lakomek, M Gahr, J Fiechtl, W Schröter.   

Abstract

The rheological properties of erythrocytes of 47 diabetic children and adolescents were studied. Deformability of red cells of 32 patients under "poor" metabolic control was markedly decreased while the deformability of red cells of patients (15 individuals) under "good" control was normal. This diminished flexibility of erythrocytes of patients under "poor" control can be explained partly by an increased concentration of free fatty acids in plasma. Moreover we found a decreased fluidity of the intracellular hemoglobin caused possibly by a decreased concentration of 2, 3-diphosphoglycerate in the cells.

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Year:  1981        PMID： 7260405     DOI： 10.1007/BF00320473

Source DB:  PubMed          Journal:  Blut        ISSN： 0006-5242


  8 in total

1.  Relationship of blood protein composition to intravascular erythrocyte aggregation (sludged blood); clinical and experimental studies.

Authors:  J DITZEL
Journal:  Acta Med Scand Suppl       Date:  1959

2.  Letters: Plasma Pi and erythrocyte 2,3-diphosphoglycerate concentrations of non-acidotic diabetics in various degrees of metabolic control.

Authors:  J Ditzel; E Standl
Journal:  Clin Chem       Date:  1976-04       Impact factor: 8.327

3.  A simple method for measuring red cell deformability in models of the microcirculation.

Authors:  H Schmid-Schönbein; J Weiss; H Ludwig
Journal:  Blut       Date:  1973-06

4.  A modified method for the determination of 2,3-diphosphoglycerate in erythrocytes.

Authors:  A Ericson; C H de Verdier
Journal:  Scand J Clin Lab Invest       Date:  1972-02       Impact factor: 1.713

5.  Red-cell aggregation and red-cell deformability in diabetes.

Authors:  H Schmid-Schönbein; E Volger
Journal:  Diabetes       Date:  1976       Impact factor: 9.461

6.  Rheological properties of erythrocytes in heterozygous and homozygous beta thalassaemia.

Authors:  W Tillmann; W Schröter
Journal:  Br J Haematol       Date:  1979-11       Impact factor: 6.998

7.  The interaction of 2,3-diphosphoglycerate with various human hemoglobins.

Authors:  H F Bunn; R W Briehl
Journal:  J Clin Invest       Date:  1970-06       Impact factor: 14.808

8.  Glycosylated hemoglobins and their relation to the control of juvenile diabetes mellitus.

Authors:  W Schröter; E Jentsch; B Stumpf; R Kubel; E Turner-Heckmann; M Gahr
Journal:  Helv Paediatr Acta       Date:  1978-12
  8 in total
  2 in total

1.  Aggregate formation of erythrocytes and diabetic retinopathy in children, adolescents, and adults with diabetes mellitus (type I).

Authors:  W Tillmann; M Lakomek; P Heidemann; W Behrens-Baumann; W Schröter
Journal:  Klin Wochenschr       Date:  1984-12-03

2.  The impact of the HbA1c level of type 2 diabetics on the structure of haemoglobin.

Authors:  Shaoying Ye; Ping Ruan; Junguang Yong; Hongtao Shen; Zhihong Liao; Xiaolei Dong
Journal:  Sci Rep       Date:  2016-09-14       Impact factor: 4.379
  2 in total

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