Literature DB >> 7260175

Effect of whole-body gamma irradiation on lipid peroxidation in rat tissues.

J F Kergonou, P Bernard, M Braquet, G Rocquet.   

Abstract

In this work, we studied the influence of whole-body gamma irradiation (800 rads) upon malonaldehyde (MDA) content in plasma, erythrocyte, brain, heart, lung, kidney, spleen, liver, thymus and bone marrow. MDA levels were increased in all studied samples, except lung; the highest increases were observed in the most radiosensitive organs (bone marrow, thymus, spleen) and not in those continuously exposed to high concentrations of molecular oxygen (lungs, erythrocytes). Comparison of the variations of MDA levels in plasma, kidneys and spleen to those in the other tissues lead to the hypothesis that MDA is released from tissues in plasma and trapped from plasma in kidney and spleen. The variations in plasma and erythrocyte were found not to be related to each other.

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Year:  1981        PMID： 7260175     DOI： 10.1016/s0300-9084(81)80088-0

Source DB:  PubMed          Journal:  Biochimie        ISSN： 0300-9084            Impact factor:   4.079


  5 in total

1.  Oxidative lipidomics of γ-radiation-induced lung injury: mass spectrometric characterization of cardiolipin and phosphatidylserine peroxidation.

Authors:  Yulia Y Tyurina; Vladimir A Tyurin; Valentyna I Kapralova; Karla Wasserloos; Mackenzie Mosher; Michael W Epperly; Joel S Greenberger; Bruce R Pitt; Valerian E Kagan
Journal:  Radiat Res       Date:  2011-02-21       Impact factor: 2.841

2.  Long term treatment with theophylline increases malonyl dialdehyde plasma concentrations.

Authors:  P Godard; J Chaintreuil; J Bensadoun; G Parelon; A C de Paulet; F B Michel
Journal:  Thorax       Date:  1984-02       Impact factor: 9.139

3.  Acute 60Co-gamma irradiation of rats decreases the inhibitory effect of succinate on the lipid peroxidation of liver mitochondria.

Authors:  E Rónai; L Mészáros; G Benkö; I Horváth
Journal:  Experientia       Date:  1984-12-15

4.  Azithromycin attenuates acute radiation-induced lung injury in mice.

Authors:  Fei Tang; Rui Li; Jianxin Xue; Jie Lan; He Xu; Yongmei Liu; Lin Zhou; You Lu
Journal:  Oncol Lett       Date:  2017-08-24       Impact factor: 2.967

5.  Watermelon (Citrullus lanatus (Thunb.) Matsum. and Nakai) juice modulates oxidative damage induced by low dose X-ray in mice.

Authors:  Mohd Khairul Amran Mohammad; Muhamad Idham Mohamed; Ainul Mardhiyah Zakaria; Hairil Rashmizal Abdul Razak; Wan Mazlina Md Saad
Journal:  Biomed Res Int       Date:  2014-04-29       Impact factor: 3.411
  5 in total

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