Literature DB >> 7259484

[Addiction-like behavior with continuous self-stimulation of the mediothalamic system (author's transl)].

B Schmidt, G Richter-Rau, U Thoden.   

Abstract

In a patient with postamputation pain a continuous self-stimulation of the mediothalamic system by a chronic deep brain electrode induced a change in behavior, similar to addiction. At the same time various psychological tests (HAWIE, Benton, Hooper-VOT and concentration tests) were significantly disturbed. After interruption of the deep brain stimulation all induced psychic abnormalities normalized within a few days.

Entities:  

Mesh：

Year:  1981        PMID： 7259484     DOI： 10.1007/bf00343767

Source DB:  PubMed          Journal:  Arch Psychiatr Nervenkr (1970)


  13 in total

1.  Positive reinforcement induced by intracerebral stimulation in the monkey.

Authors:  B BURSTEN; J M DELGADO
Journal:  J Comp Physiol Psychol       Date:  1958-02

2.  Self-stimulation of the brain; its use to study local effects of hunger, sex, and drugs.

Authors:  J OLDS
Journal:  Science       Date:  1958-02-14       Impact factor: 47.728

3.  Positive reinforcement produced by electrical stimulation of septal area and other regions of rat brain.

Authors:  J OLDS; P MILNER
Journal:  J Comp Physiol Psychol       Date:  1954-12

Review 4.  [Endorphin--endogenous peptides with morphine-like effects. 1. Methods for detection, structural characteristics, incidence, effects].

Authors:  W Kromer
Journal:  Fortschr Med       Date:  1978-07-27

5.  Pain reduction by electrical brain stimulation in man. Part 2: Chronic self-administration in the periventricular gray matter.

Authors:  D E Richardson; H Akil
Journal:  J Neurosurg       Date:  1977-08       Impact factor: 5.115

6.  Medial thalamic permanent electrodes for pain control in man: an electrophysiological and clinical study.

Authors:  U Thoden; M Doerr; G Dieckmann; J U Krainick
Journal:  Electroencephalogr Clin Neurophysiol       Date:  1979-11

7.  Relief of pain by electrical stimulation of the septal area.

Authors:  A Gol
Journal:  J Neurol Sci       Date:  1967 Jul-Aug       Impact factor: 3.181

8.  Pain reduction by electrical brain stimulation in man. Part 1: Acute administration in periaqueductal and periventricular sites.

Authors:  D E Richardson; H Akil
Journal:  J Neurosurg       Date:  1977-08       Impact factor: 5.115

9.  Enkephalin-like material elevated in ventricular cerebrospinal fluid of pain patients after analgetic focal stimulation.

Authors:  H Akil; D E Richardson; J Hughes; J D Barchas
Journal:  Science       Date:  1978-08-04       Impact factor: 47.728

10.  Pain reduction in amputees by long-term spinal cord stimulation. Long-term follow-up study over 5 years.

Authors:  J U Krainick; U Thoden; T Riechert
Journal:  J Neurosurg       Date:  1980-03       Impact factor: 5.115
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