Literature DB >> 7257870

Lactic acidosis during metformin treatment in an elderly diabetic patient with impaired renal function.

L S Hermann, S Magnusson, B Möller, C Casey, G T Tucker, H F Woods.   

Abstract

In recent years, lactic acidosis has been described in association with metformin therapy in diabetics. We report a fatal case in an elderly diabetic patient with impaired renal function and cardiac insufficiency. The patient presented with an elevated plasma metformin concentration and a concomitant digitoxin intoxication.

Entities:  

Mesh:

Substances:

Year:  1981        PMID: 7257870     DOI: 10.1111/j.0954-6820.1981.tb11639.x

Source DB:  PubMed          Journal:  Acta Med Scand        ISSN: 0001-6101


  4 in total

1.  Fatal metformin overdose: case report and postmortem biochemistry contribution.

Authors:  Alessandro Bonsignore; Fulvia Pozzi; Giulio Fraternali Orcioni; Francesco Ventura; Cristian Palmiere
Journal:  Int J Legal Med       Date:  2013-11-08       Impact factor: 2.686

2.  Metformin and glibenclamide: comparative risks.

Authors:  I W Campbell
Journal:  Br Med J (Clin Res Ed)       Date:  1984-08-04

3.  The Association between Metformin Therapy and Lactic Acidosis.

Authors:  Isabelle H S Kuan; Ruth L Savage; Stephen B Duffull; Robert J Walker; Daniel F B Wright
Journal:  Drug Saf       Date:  2019-12       Impact factor: 5.606

Review 4.  Pharmacokinetic-pharmacodynamic relationships of oral hypoglycaemic agents. An update.

Authors:  P Marchetti; R Navalesi
Journal:  Clin Pharmacokinet       Date:  1989-02       Impact factor: 6.447

  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.