Literature DB >> 7257348

Abnormal aminopyrine metabolism in patients with chronic hepatitis.

G W Hepner, E Piken, J Lechago.   

Abstract

Aminopyrine metabolism was studied by the aminopyrine breath test in 21 control subjects, 24 patients with untreated chronic active hepatitis (CAH), 4 patients with treated CAH and 17 patients with chronic persistent hepatitis (CPH). Aminopyrine breath tests gave abnormal results in 20 of 24 patients with untreated CAH. Findings were normal in all patients with treated CAH or with CPH. This test may be helpful in discriminating between CAH and other forms of chronic hepatitis.

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Year:  1981        PMID： 7257348      PMCID： PMC1272763     

Source DB:  PubMed          Journal:  West J Med        ISSN： 0093-0415


  16 in total

1.  Assessment of aminopyrine metabolism in man by breath analysis after oral administration of 14C-aminopyrine. Effects of phenobarbital, disulfiram and portal cirrhosis.

Authors:  G W Hepner; E S Vesell
Journal:  N Engl J Med       Date:  1974-12-26       Impact factor: 91.245

2.  Controlled trial of prednisone and azathioprine in active chronic hepatitis.

Authors:  I M Murray-Lyon; R B Stern; R Williams
Journal:  Lancet       Date:  1973-04-07       Impact factor: 79.321

3.  Clinical, biochemical, and histological remission of severe chronic active liver disease: a controlled study of treatments and early prognosis.

Authors:  R D Soloway; W H Summerskill; A H Baggenstoss; M G Geall; G L Gitnićk; I R Elveback; L J Schoenfield
Journal:  Gastroenterology       Date:  1972-11       Impact factor: 22.682

4.  Controlled prospective trial of corticosteroid therapy in active chronic hepatitis.

Authors:  G C Cook; R Mulligan; S Sherlock
Journal:  Q J Med       Date:  1971-04

5.  Observer error and sampling variability tested in evaluation of hepatitis and cirrhosis by liver biopsy.

Authors:  R D Soloway; A H Baggenstoss; L J Schoenfield; W H Summerskill
Journal:  Am J Dig Dis       Date:  1971-12

6.  Kinetics of CO2-HCO3 minus in normal adult males.

Authors:  H S Winchell; H Stahelin; N Kusubov; B Slanger; M Fish; M Pollycove; J H Lawrence
Journal:  J Nucl Med       Date:  1970-12       Impact factor: 10.057

7.  Corticosteroid therapy for chronic active hepatitis.

Authors:  P D Berk; E A Jones; P H Plotz; L B Seeff; E C Wright
Journal:  Ann Intern Med       Date:  1976-10       Impact factor: 25.391

8.  Quantitative assessment of hepatic function by breath analysis after oral administration of (14C)aminopyrine.

Authors:  G W Hepner; E S Vesell
Journal:  Ann Intern Med       Date:  1975-11       Impact factor: 25.391

9.  Aminopyrine demethylation measured by breath analysis in cirrhosis.

Authors:  J Bircher; A Küpfer; I Gikalov; R Preisig
Journal:  Clin Pharmacol Ther       Date:  1976-10       Impact factor: 6.875

10.  Abnormal aminopyrine metabolism in patients with hepatic neoplasm. Detection by breath test.

Authors:  G W Hepner; S R Uhlin; A Lipton; H A Harvey; V Rohrer
Journal:  JAMA       Date:  1976-10-04       Impact factor: 56.272
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  1 in total

1.  [14C]Aminopyrine breath test in chronic liver disease: preliminary diagnostic implications.

Authors:  A V Burnstein; J T Galambos
Journal:  Dig Dis Sci       Date:  1981-12       Impact factor: 3.199
  1 in total

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