Literature DB >> 7257183

Genetic factors associated with loss of the temperature-sensitive phenotype of the influenza A/Alaska/77-ts-1A2 recombinant during growth in vivo.

M D Tolpin, J G Massicot, M G Mullinix, H W Kim, R H Parrott, R M Chanock, B R Murphy.   

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Year:  1981        PMID： 7257183     DOI： 10.1016/0042-6822(81)90298-1

Source DB:  PubMed          Journal:  Virology        ISSN： 0042-6822            Impact factor:   3.616


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  16 in total

1.  Codon substitution mutations at two positions in the L polymerase protein of human parainfluenza virus type 1 yield viruses with a spectrum of attenuation in vivo and increased phenotypic stability in vitro.

Authors:  Josephine M McAuliffe; Sonja R Surman; Jason T Newman; Jeffrey M Riggs; Peter L Collins; Brian R Murphy; Mario H Skiadopoulos
Journal:  J Virol       Date:  2004-02       Impact factor: 5.103

2.  Evaluation of bovine, cold-adapted human, and wild-type human parainfluenza type 3 viruses in adult volunteers and in chimpanzees.

Authors:  M L Clements; R B Belshe; J King; F Newman; T U Westblom; E L Tierney; W T London; B R Murphy
Journal:  J Clin Microbiol       Date:  1991-06       Impact factor: 5.948

3.  Recombinant respiratory syncytial virus (RSV) bearing a set of mutations from cold-passaged RSV is attenuated in chimpanzees.

Authors:  S S Whitehead; K Juhasz; C Y Firestone; P L Collins; B R Murphy
Journal:  J Virol       Date:  1998-05       Impact factor: 5.103

4.  Engineering temperature sensitive live attenuated influenza vaccines from emerging viruses.

Authors:  Bin Zhou; Yan Li; Scott D Speer; Anju Subba; Xudong Lin; David E Wentworth
Journal:  Vaccine       Date:  2012-03-24       Impact factor: 3.641

5.  Four viral genes independently contribute to attenuation of live influenza A/Ann Arbor/6/60 (H2N2) cold-adapted reassortant virus vaccines.

Authors:  M H Snyder; R F Betts; D DeBorde; E L Tierney; M L Clements; D Herrington; S D Sears; R Dolin; H F Maassab; B R Murphy
Journal:  J Virol       Date:  1988-02       Impact factor: 5.103

6.  Evaluation of the genetic stability of the temperature-sensitive PB2 gene mutation of the influenza A/Ann Arbor/6/60 cold-adapted vaccine virus.

Authors:  J Treanor; M Perkins; R Battaglia; B R Murphy
Journal:  J Virol       Date:  1994-12       Impact factor: 5.103

7.  Rescue of an influenza A virus wild-type PB2 gene and a mutant derivative bearing a site-specific temperature-sensitive and attenuating mutation.

Authors:  E K Subbarao; Y Kawaoka; B R Murphy
Journal:  J Virol       Date:  1993-12       Impact factor: 5.103

8.  Evaluation of a phenotypic revertant of the A/Alaska/77-ts-1A2 reassortant virus in hamsters and in seronegative adult volunteers: further evidence that the temperature-sensitive phenotype is responsible for attenuation of ts-1A2 reassortant viruses.

Authors:  M D Tolpin; M L Clements; M M Levine; R E Black; A J Saah; W C Anthony; L Cisneros; R M Chanock; B R Murphy
Journal:  Infect Immun       Date:  1982-05       Impact factor: 3.441

9.  Evaluation of a live attenuated, cold-adapted parainfluenza virus type 3 vaccine in children.

Authors:  R B Belshe; R A Karron; F K Newman; E L Anderson; S L Nugent; M Steinhoff; M L Clements; M H Wilson; S L Hall; E L Tierney
Journal:  J Clin Microbiol       Date:  1992-08       Impact factor: 5.948

10.  Studies of the major reovirus core protein sigma 2: reversion of the assembly-defective mutant tsC447 is an intragenic process and involves back mutation of Asp-383 to Asn.

Authors:  K M Coombs; S C Mak; L D Petrycky-Cox
Journal:  J Virol       Date:  1994-01       Impact factor: 5.103
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