Literature DB >> 7256283

Range of radiochemical damage to DNA with decay of iodine-125.

R F Martin, W A Haseltine.   

Abstract

Studies of the length of DNA fragments produced upon decay of iodine-125-labeled deoxycytidine that was located at a single position within a DNA fragment of defined sequence demonstrate that most radiochemical damage occurs within 15 to 20 angstroms of the site of iodine-125 decay. However, DNA strand breakage was detectable up to 70 angstroms from the site of iodine-125 decay.

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Year:  1981        PMID: 7256283     DOI: 10.1126/science.7256283

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  29 in total

1.  Effect of distance between decaying (125)I and DNA on Auger-electron induced double-strand break yield.

Authors:  Pichumani Balagurumoorthy; Xiang Xu; Ketai Wang; S James Adelstein; Amin I Kassis
Journal:  Int J Radiat Biol       Date:  2012-07-24       Impact factor: 2.694

2.  Study of charge transport mechanisms in (125)I-induced DNA damage at various temperatures.

Authors:  Thabisile Ndlebe; Ronald D Neumann; Igor G Panyutin
Journal:  Int J Radiat Biol       Date:  2012-06-25       Impact factor: 2.694

3.  Molecular and cellular radiobiological effects of Auger emitting radionuclides.

Authors:  Amin I Kassis
Journal:  Radiat Prot Dosimetry       Date:  2010-11-24       Impact factor: 0.972

Review 4.  Auger electron emitters: insights gained from in vitro experiments.

Authors:  G Makrigiorgos; S J Adelstein; A I Kassis
Journal:  Radiat Environ Biophys       Date:  1990       Impact factor: 1.925

Review 5.  What are the risks of low-level exposure to alpha radiation from radon?

Authors:  J B Little
Journal:  Proc Natl Acad Sci U S A       Date:  1997-06-10       Impact factor: 11.205

6.  Radioprobing of DNA: distribution of DNA breaks produced by decay of 125I incorporated into a triplex-forming oligonucleotide correlates with geometry of the triplex.

Authors:  I G Panyutin; R D Neumann
Journal:  Nucleic Acids Res       Date:  1997-02-15       Impact factor: 16.971

7.  Molecular analysis of base damage clustering associated with a site-specific radiation-induced DNA double-strand break.

Authors:  Kamal Datta; Pawel Jaruga; Miral Dizdaroglu; Ronald D Neumann; Thomas A Winters
Journal:  Radiat Res       Date:  2006-11       Impact factor: 2.841

8.  Sequence-specific DNA double-strand breaks induced by triplex forming 125I labeled oligonucleotides.

Authors:  I G Panyutin; R D Neumann
Journal:  Nucleic Acids Res       Date:  1994-11-25       Impact factor: 16.971

9.  Assessing DNA structures with 125I radioprobing.

Authors:  Timur I Gaynutdinov; Ronald D Neumann; Igor G Panyutin
Journal:  Methods Mol Biol       Date:  2010

10.  Some factors affecting the sensitivity of cultured human cells to high-LET radiation.

Authors:  D K Myers; N E Gentner
Journal:  Radiat Environ Biophys       Date:  1987       Impact factor: 1.925

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