Literature DB >> 7254779

Experimental model of gyrate atrophy in animals.

T Kuwabara, Y Ishikawa, M I Kaiser-Kupfer.   

Abstract

Intravitreal injection of L-ornithine hydrochloride in physiologic saline solution caused marked edema specifically in the pigment epithelium of Sprague-Dawley strain albino and Evans black hooded rats and rhesus and cynomologus monkeys. Swelling of the pigment epithelial cells, which was most prominent four hours after the injection, disappeared by 24 hours. However, many pigment epithelial cells gradually degenerated resulting in patches of denuded areas. The photoreceptor cells overlying the damaged pigment epithelium degenerated secondarily.

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Year:  1981        PMID： 7254779     DOI： 10.1016/s0161-6420(81)35027-1

Source DB:  PubMed          Journal:  Ophthalmology        ISSN： 0161-6420            Impact factor:   12.079


  11 in total

Review 1.  Molecular ophthalmology: an update on animal models for retinal degenerations and dystrophies.

Authors:  F Hafezi; C Grimm; B C Simmen; A Wenzel; C E Remé
Journal:  Br J Ophthalmol       Date:  2000-08       Impact factor: 4.638

2.  Progression of gyrate atrophy measured with ultra-wide-field imaging.

Authors:  Guillermo Salcedo-Villanueva; Miguel Paciuc-Beja; Cristina Villanueva-Mendoza; Mariana Harasawa; Jesse M Smith; Raul Velez-Montoya; Jeffrey L Olson; Scott C Oliver; Naresh Mandava; Hugo Quiroz-Mercado
Journal:  Int Ophthalmol       Date:  2015-05-26       Impact factor: 2.031

3.  The Kearns-Sayre syndrome: a light and electron microscopic study.

Authors:  R C Eagle; T R Hedges; M Yanoff
Journal:  Trans Am Ophthalmol Soc       Date:  1982

Review 4.  Endogenous ornithine in search for CNS functions and therapeutic applications.

Authors:  N Seiler; G Daune-Anglard
Journal:  Metab Brain Dis       Date:  1993-09       Impact factor: 3.584

5.  Low-protein diet and progression of retinal degeneration in gyrate atrophy of the choroid and retina: a twenty-six-year follow-up.

Authors:  R Santinelli; C Costagliola; C Tolone; A D'Aloia; A D'Avanzo; F Prisco; L Perrone; E Miraglia del Giudice
Journal:  J Inherit Metab Dis       Date:  2004       Impact factor: 4.982

6.  Gyrate atrophy of the choroid and retina: ERG of the neural retina and the pigment epithelium.

Authors:  C Raitta; S Carlson; K Vannas-Sulonen
Journal:  Br J Ophthalmol       Date:  1990-06       Impact factor: 4.638

7.  Cystoid macular edema secondary to gyrate atrophy in a child treated with sub-tenon injection of triamcinolone acetonide.

Authors:  Şahin Alparslan; Mehmet Türkcü Fatih; Şahin Muhammed; Yıldırım Adnan
Journal:  Rom J Ophthalmol       Date:  2018 Jul-Sep

Review 8.  Potential of Induced Pluripotent Stem Cells (iPSCs) for Treating Age-Related Macular Degeneration (AMD).

Authors:  Mark Fields; Hui Cai; Jie Gong; Lucian Del Priore
Journal:  Cells       Date:  2016-12-08       Impact factor: 6.600

9.  Gyrate atrophy-like phenotype with normal plasma ornithine and low plasma taurine.

Authors:  Aubhugn T Labiano; Milagros H Arroyo
Journal:  GMS Ophthalmol Cases       Date:  2020-02-27

Review 10.  Epigenetics in age-related macular degeneration: new discoveries and future perspectives.

Authors:  M Gemenetzi; A J Lotery
Journal:  Cell Mol Life Sci       Date:  2020-01-02       Impact factor: 9.261
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