[On the prognostic value of the 1-h level in the glucose tolerance test. (Five year follow-up with long-term hospitalised psychiatric patients) (author's transl)].

In 922 long-term hospitalised psychiatric patients the glucose tolerance war examined by 1-h level after oral glucose during a five year follow-up study on cardio-vascular risk factors. We were unable to determine the future development of metabolism with reference to normal findings of the test, borderlines levels ans positively impaired glucose tolerance. But it was to be seen than depending on increasing basic levels the tendency towards a decrease in glucose tolerance increased too. As far as prognosis is concerned, a turning-point for the further development either towards a return to normal or a manifest diabetes seems to be at 180 mg% after 1 h. Above this level, the probability to develop manifest diabetes respectively a higher degree of impaired tolerance has become within a few years, just as great as the probability of a remission. The tendency towards a decreasing glucose tolerance or the manifestation of diabetes was furthered by initial existence or development of a higher overweight (more than 30%).