[Pattern quantification of coronary artery stenosis by computerized analysis of multiple ECG parameters (author's transl)].

Coronary angiograms of 200 patients with coronary artery disease were studied. The distribution of stenoses was analyzed and classified utilizing a special score, taking into account coronary supply pattern (according to Baroldi et al.), localization and severity of stenosis, as well as collateralization. Frank-lead vectorcardiograms were obtained and analyzed by computer. 140 scalar and spatial vector parameters were evaluated. A statistical comparison was made in 36 patients with highgrade stenoses of the left anterior descending branch of the left coronary artery with 37 patients without such vascular narrowing. Utilizing 4 ECG-parameters a mathematical formula can be derived which separates the two groups. Another equation based on 5 parameters allows the calculation of a score from conventional electrocardiograms. By discriminance analysis a specificity of 78.4% and a sensibility of 77.8 in prediction results for the group with stenosis. For the control group a specificity of 75.7% and a sensibility of 77.8% were computed. Correlation between the score obtained by calculation on the one hand, and the score derived from direct analysis of the arteriogram was highly significant with an r = 0.796.