| Literature DB >> 7251054 |
Abstract
The binding parameters of chemically-defined immune complexes composed of rat IgGa-anti-human serum albumin (HSA) to rat basophilic leukaemia cells were analysed. It was demonstrated that the uptake of various sized immune complexes is time-, temperature- and pH-dependent. A higher binding rate was observed with more Fc portions available in the immune complex. A comparison of the binding rate for immune complexes with that of heat aggregates shows that immune complexes bind with greater affinity to the cells.Entities:
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Year: 1981 PMID: 7251054 PMCID: PMC1555005
Source DB: PubMed Journal: Immunology ISSN: 0019-2805 Impact factor: 7.397