Literature DB >> 7250331

Bioavailability of progesterone enhanced by intranasal spraying.

G F David, C P Puri, T C Anand Kumar.   

Abstract

The bioavailability of progesterone (P) in terms of area under time-concentration curve and maximal concentration in the serum and cerebrospinal fluid was studied in adult ovariectomized rhesus monkeys following the administration of P as a nasal spray, i.v. or i.m. injections, nasal or eye drops. The bioavailability of P in both the body fluids was found to be considerably higher following its being sprayed intranasally.

Entities:  

Mesh：

Substances：

Year:  1981        PMID： 7250331     DOI： 10.1007/bf01986182

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  6 in total

1.  Effects of progestational compounds on the reproductive processes of the human male.

Authors:  C G HELLER; W M LAIDLAW; H T HARVEY; W O NELSON
Journal:  Ann N Y Acad Sci       Date:  1958-07-30       Impact factor: 5.691

2.  Ovulation in rhesus monkeys suppressed by intranasal administration of progesterone and norethisterone.

Authors:  T C Anand Kumar; G F David; V Puri
Journal:  Nature       Date:  1977-12-08       Impact factor: 49.962

3.  The World Health Organization's programme for the standardization and quality control of radioimmunoassay of hormones in reproductive physiology.

Authors:  P E Hall
Journal:  Horm Res       Date:  1978

4.  Levels of estradiol and progesterone in the cerebrospinal fluid of rhesus monkey during the menstrual cycle.

Authors:  T C Kumar; G F David; V Puri
Journal:  J Med Primatol       Date:  1980       Impact factor: 0.667

5.  Selection and pairing of 'normal' rhesus monkeys (Macaca mulatta) for research: procedures, techniques, and observations.

Authors:  M J Kessler; J L Kupper; J D Grissett; R J Brown
Journal:  J Med Primatol       Date:  1979       Impact factor: 0.667

6.  Effects of intranasal administration of hormonal steroids on serum testosterone and spermatogenesis in rhesus monkey (Macaca mulatta).

Authors:  T C Anand Kumar; A Sehgal; G F David; J S Bajaj; M R Prasad
Journal:  Biol Reprod       Date:  1980-05       Impact factor: 4.285
  6 in total
  2 in total

1.  Drug absorption through mucosal membranes: effect of mucosal route and penetrant hydrophilicity.

Authors:  D C Corbo; J C Liu; Y W Chien
Journal:  Pharm Res       Date:  1989-10       Impact factor: 4.200

2.  Menstrual synchrony : An update and review.

Authors:  C A Graham
Journal:  Hum Nat       Date:  1991-12
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.