Literature DB >> 7250306

Induction and development of mouse liver glutathione S-transferase activity.

D D Shoemaker, D D Dietrick, R L Cysyk.   

Abstract

Mouse liver glutathione S-transferase activity at birth was 1/10 that of adults, and increased steadily with each successive week of age until adult values were reached at 8 weeks. Activity was inducible with phenobarbital; however, the percentage increase in activity was dependent upon substrate. 2 distinct peaks of transferase activity were obtained on CM-cellulose chromatography. The ratios of transferase activity observed for each peak demonstrated that glutathione S-transferase activity in mouse liver is associated with at least 2 distinct proteins with differing substrate specificities.

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Year:  1981        PMID： 7250306     DOI： 10.1007/bf01986122

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  15 in total

1.  Maturation of the sulfobromophthalein sodium-glutathione conjugating system in rat liver.

Authors:  B COMBES; G S STAKELUM
Journal:  J Clin Invest       Date:  1962-04       Impact factor: 14.808

2.  Elevation of hepatic glutathione S-transferase activities and protection against mutagenic metabolites of benzo(a)pyrene by dietary antioxidants.

Authors:  A M Benson; R P Batzinger; S Y Ou; E Bueding; Y N Cha; P Talalay
Journal:  Cancer Res       Date:  1978-12       Impact factor: 12.701

3.  Glutathione S-transferase A. A novel kinetic mechanism in which the major reaction pathway depends on substrate concentration.

Authors:  M J Pabst; W H Habig; W B Jakoby
Journal:  J Biol Chem       Date:  1974-11-25       Impact factor: 5.157

4.  Glutathione S-transferases. The first enzymatic step in mercapturic acid formation.

Authors:  W H Habig; M J Pabst; W B Jakoby
Journal:  J Biol Chem       Date:  1974-11-25       Impact factor: 5.157

5.  Mercapturic acid formation: the several glutathione transferases of rat liver.

Authors:  M J Pabst; W H Habig; W B Jakoby
Journal:  Biochem Biophys Res Commun       Date:  1973-06-19       Impact factor: 3.575

Review 6.  The role of glutathione and glutathione S-transferases in mercapturic acid biosynthesis.

Authors:  E Boyland; L F Chasseaud
Journal:  Adv Enzymol Relat Areas Mol Biol       Date:  1969

7.  Separate identities of ligandin and the h-protein, a major protein to which carcinogenic hydrocarbons are covalently bound.

Authors:  A M Sarrif; P V Danenberg; C Heidelberger
Journal:  Biochem Biophys Res Commun       Date:  1976-06-07       Impact factor: 3.575

8.  Drug induction of hepatic glutathione S-transferases in male and female rats*.

Authors:  N Kaplowitz; J Kuhlekamp; G Clifton
Journal:  Biochem J       Date:  1975-02       Impact factor: 3.857

9.  Developmental aspects of glutathione S-transferase B (ligandin) in rat liver.

Authors:  B F Hales; A H Neims
Journal:  Biochem J       Date:  1976-11-15       Impact factor: 3.857

10.  Separation of glutathione S-transferase activities with epoxides from the mouse liver h-protein, a major polycyclic hydrocarbon-binding protein.

Authors:  A M Sarrif; K L McCarthy; S Nesnow; C Heidelberger
Journal:  Cancer Res       Date:  1978-05       Impact factor: 12.701
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  1 in total

1.  Glutathione S-transferase in humans: development and tissue distribution.

Authors:  G M Pacifici; M Franchi; C Colizzi; L Giuliani; A Rane
Journal:  Arch Toxicol       Date:  1988       Impact factor: 5.153
  1 in total

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