Literature DB >> 7250305

Studies on the inactivation of glyceraldehyde-3-phosphate dehydrogenase by methylglyoxal.

G Leoncini, M Maresca, S Ronchi, A Bonsignore.   

Abstract

Glyceraldehyde-3-P dehydrogenase (E.C. 1.2.1.12) from rabbit muscle is rapidly inactivated by methylglyoxal following pseudo first-order kinetics. Substrate, as well as inorganic phosphate, affords protection, whereas NAD+ is ineffective. The arginine residue implicated in the reaction is probably the anion binding site of the phosphate group of the substrate.

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Year:  1981        PMID: 7250305     DOI: 10.1007/bf01986121

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  12 in total

1.  Esters of methanesulfonic acid as irreversible inhibitors of acetylcholinesterase.

Authors:  R KITZ; I B WILSON
Journal:  J Biol Chem       Date:  1962-10       Impact factor: 5.157

2.  Tissue sulfhydryl groups.

Authors:  G L ELLMAN
Journal:  Arch Biochem Biophys       Date:  1959-05       Impact factor: 4.013

3.  The coenzyme content of rabbit muscle D-glyceraldehyde-3-phosphate dehydrogenase.

Authors:  W B DANDLIKER; J B FOX
Journal:  J Biol Chem       Date:  1956-08       Impact factor: 5.157

4.  A reactive arginine in adenylate kinase.

Authors:  J Berghäuser
Journal:  Biochim Biophys Acta       Date:  1975-08-26

5.  A study on the metabolism of glyoxal in vitro.

Authors:  E KUN
Journal:  J Biol Chem       Date:  1952-02       Impact factor: 5.157

6.  The mechanism of action of glyoxalase.

Authors:  E RACKER
Journal:  J Biol Chem       Date:  1951-06       Impact factor: 5.157

7.  Functional arginine residues of D-glyceraldehyde-3-phosphate dehydrogenase from rat skeletal muscle.

Authors:  N K Nagradova; R A Asryants; N V Benekevich; M I Safronova
Journal:  FEBS Lett       Date:  1976-10-15       Impact factor: 4.124

8.  The role of arginine residues in the function of D-glyceraldehyde-3-phosphate dehydrogenase.

Authors:  N K Nagradova; R A Asryants; N V Benkevich
Journal:  Biochim Biophys Acta       Date:  1978-12-08

9.  Inhibition of L-glutamine:D-fructose-6-phosphate aminotransferase by methylglyoxal.

Authors:  H Kikuchi; Y Ikeda; S Tsuiki
Journal:  Biochim Biophys Acta       Date:  1972-12-07

10.  Studies on the interaction of fructose 1,6-P2 aldolase with methylglyoxal.

Authors:  G Leoncini; S Ronchi; M Maresca; A Bonsignore
Journal:  Ital J Biochem       Date:  1980 Jul-Aug
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  3 in total

Review 1.  Methylglyoxal and Its Adducts: Induction, Repair, and Association with Disease.

Authors:  Seigmund Wai Tsuen Lai; Edwin De Jesus Lopez Gonzalez; Tala Zoukari; Priscilla Ki; Sarah C Shuck
Journal:  Chem Res Toxicol       Date:  2022-10-05       Impact factor: 3.973

2.  Enhanced Formation of Methylglyoxal-Derived Advanced Glycation End Products in Arabidopsis Under Ammonium Nutrition.

Authors:  Klaudia Borysiuk; Monika Ostaszewska-Bugajska; Marie-Noëlle Vaultier; Marie-Paule Hasenfratz-Sauder; Bożena Szal
Journal:  Front Plant Sci       Date:  2018-05-24       Impact factor: 5.753

Review 3.  Carbonyl Stress in Red Blood Cells and Hemoglobin.

Authors:  Olga V Kosmachevskaya; Natalia N Novikova; Alexey F Topunov
Journal:  Antioxidants (Basel)       Date:  2021-02-07
  3 in total

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