Literature DB >> 7248938

Covalent binding of methotrexate to immunoglobulins and the effect of antibody-linked drug on tumor growth in vivo.

P N Kulkarni, A H Blair, T I Ghose.   

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Year:  1981        PMID: 7248938

Source DB:  PubMed          Journal:  Cancer Res        ISSN: 0008-5472            Impact factor:   12.701


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  20 in total

1.  Cytotoxicities of two disulfide-bond-linked conjugates of methotrexate with monoclonal anti-MM46 antibody.

Authors:  N Umemoto; Y Kato; T Hara
Journal:  Cancer Immunol Immunother       Date:  1989       Impact factor: 6.968

2.  Synthesis of site-specific methotrexate-IgG conjugates. Comparison of stability and antitumor activity with active-ester-based conjugates.

Authors:  J Kralovec; M Singh; M Mammen; A H Blair; T Ghose
Journal:  Cancer Immunol Immunother       Date:  1989       Impact factor: 6.968

3.  Effects of methotrexate-carcinoembryonic-antigen-antibody immunoconjugates on GW-39 human tumors in nude mice.

Authors:  L B Shih; D M Goldenberg
Journal:  Cancer Immunol Immunother       Date:  1990       Impact factor: 6.968

4.  Carbohydrate-binding proteins of tumor lines with different growth properties. II. Changes in their pattern in clones of transformed rat fibroblasts of differing metastatic potential.

Authors:  H J Gabius; K Vehmeyer; R Engelhardt; G A Nagel; F Cramer
Journal:  Cell Tissue Res       Date:  1986       Impact factor: 5.249

5.  Tissue localization of methotrexate-monoclonal-IgM immunoconjugates: anti-SSEA-1 and MOPC 104E in mouse teratocarcinomas and normal tissues.

Authors:  B Ballou; R Jaffe; S Persiani; W C Shen; J J Langone; H Sands; J M Reilandu; J Curley; T R Hakala
Journal:  Cancer Immunol Immunother       Date:  1992       Impact factor: 6.968

6.  Uptake of methotrexate linked to an anti-EL4-lymphoma antibody by EL4 cells.

Authors:  P Uadia; A H Blair; T Ghose
Journal:  Cancer Immunol Immunother       Date:  1983       Impact factor: 6.968

7.  Ricin A-chain conjugated with monoclonal anti-L1210 antibody. In vitro and in vivo antitumor activity.

Authors:  K Kishida; Y Masuho; M Saito; T Hara; H Fuji
Journal:  Cancer Immunol Immunother       Date:  1983       Impact factor: 6.968

8.  Regression of human melanoma xenografts in nude mice injected with methotrexate linked to monoclonal antibody 225.28 to human high molecular weight-melanoma associated antigen.

Authors:  T Ghose; S Ferrone; A H Blair; Y Kralovec; M Temponi; M Singh; M Mammen
Journal:  Cancer Immunol Immunother       Date:  1991       Impact factor: 6.968

9.  Conjugation of methotrexate to IgG antibodies and their F(ab)2 fragments and the effect of conjugated methotrexate on tumor growth in vivo.

Authors:  P N Kulkarni; A H Blair; T Ghose; M Mammen
Journal:  Cancer Immunol Immunother       Date:  1985       Impact factor: 6.968

10.  Antibody directed targeting of methotrexate-containing small unilamellar vesicles.

Authors:  M Singh; G Faulkner; T I Ghose; M Mezei
Journal:  Cancer Immunol Immunother       Date:  1988       Impact factor: 6.968

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