Literature DB >> 7248928

Vitamin C acts as a cocarcinogen to methylcholanthrene in guinea-pigs.

S Banic.   

Abstract

Large doses of vitamin C were found to promote the induction of sarcomas by methylcholanthrene. The tumours appeared earlier in the group of guinea-pigs treated with vitamin C after injection of methylcholanthrene than in the control group injected with methylcholanthrene. The treatment of guinea-pigs with vitamin C after induction of tumours thus did not inhibit the growth of tumours.

Entities:  

Mesh:

Substances:

Year:  1981        PMID: 7248928     DOI: 10.1016/0304-3835(81)90114-2

Source DB:  PubMed          Journal:  Cancer Lett        ISSN: 0304-3835            Impact factor:   8.679


  2 in total

1.  Hydroxylation of deoxyguanosine at the C-8 position by ascorbic acid and other reducing agents.

Authors:  H Kasai; S Nishimura
Journal:  Nucleic Acids Res       Date:  1984-02-24       Impact factor: 16.971

2.  Biochemical changes associated with ascorbic acid-cisplatin combination therapeutic efficacy and protective effect on cisplatin-induced toxicity in tumor-bearing mice.

Authors:  Amenla Longchar; Surya Bali Prasad
Journal:  Toxicol Rep       Date:  2015-02-07
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.