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Literature DB >> 7247463

Electron microscopy findings in fetal organs after perfusion of the amniotic cavity with oxygenated fluorocarbon.

Abstract

In 20 fetal rabbits a double-blind electron microscopy study of placenta, lung, heart, liver, and stomach was performed at 28 or 29 days of gestation. The amniotic cavity was continuously perfused with perfluorotetrahydrofuran (FC 77) before the fetuses were killed. Compared with control fetuses, no morphological changes of fetal lung and stomach nor of placenta related to FC were found. There were unexplained changes in liver parenchymal cells. However, a protective effect of FC on the myocardial tissue was observed.

Entities: Chemical Species

Mesh：

Substances：
Fluorocarbons

Year: 1981 PMID： 7247463 DOI： 10.1007/bf02111801

Source DB: PubMed Journal: Arch Gynecol ISSN： 0170-9925

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References

13 in total

Review 10. [Perfluorochemical-emulsion (fluorocarbon-43) as blood gas carrier--fate of the substance after intravenous injection in rat (author's transl)].

Authors: F Pfannkuch; N Schnoy
Journal: Anaesthesist Date: 1979-11 Impact factor: 1.041

Electron microscopy findings in fetal organs after perfusion of the amniotic cavity with oxygenated fluorocarbon.

1. Perfluorocarbon emulsions in the perfusion of canine organs.

2. Blood gas transport of fluorocarbon emulsion and its effect on the metabolism in peripheral tissue.

3. Pulmonary function after ventilation with fluorocarbon liquid (Caroxin-D).

4. Survival and histopathologic changes in lungs of hamsters following synthetic liquid breathing.

5. Suppression of fetal breathing to prevent aspiration of meconium.

6. Oxygenation by ventilation with fluorocarbon liquid (FX-80).

7. Residual levels and biochemical changes after ventilation with perfluorinated liquid.

8. Emulsions of perfluorinated solvents for intravascular gas transport.

9. Alterations of liver and spleen following intravenous infusion of fluorocarbon emulsions.

Review 10. [Perfluorochemical-emulsion (fluorocarbon-43) as blood gas carrier--fate of the substance after intravenous injection in rat (author's transl)].