Literature DB >> 7246988

Rectal premedication in children. Use of diazepam, morphine and hyoscine.

S Lindahl, A K Olsson, D Thomson.   

Abstract

Rectal premedication with diazepam, morphine and hyoscine has been used in 20 healthy children undergoing minor surgery. Satisfactory sedation was achieved in the majority of children and the anticholinergic effects were also adequate. Peak plasma levels of diazepam and morphine were reached within 30 minutes, and the plasma levels decreased after 2 hours. No adverse effects on ventilation were seen during anaesthesia.

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Year:  1981        PMID: 7246988     DOI: 10.1111/j.1365-2044.1981.tb10241.x

Source DB:  PubMed          Journal:  Anaesthesia        ISSN: 0003-2409            Impact factor:   6.955


  12 in total

1.  Fatal outcome with use of rectal morphine for postoperative pain control in an infant.

Authors:  G K Gourlay; R A Boas
Journal:  BMJ       Date:  1992-03-21

2.  Giving drugs per rectum for systemic effect.

Authors:  I A Choonara
Journal:  Arch Dis Child       Date:  1987-08       Impact factor: 3.791

Review 3.  Anaesthetic premedication: aims, assessment and methods.

Authors:  T H Madej; R T Paasuke
Journal:  Can J Anaesth       Date:  1987-05       Impact factor: 5.063

4.  Drastic improvement in the rectal absorption profile of morphine in man.

Authors:  F Moolenaar; J P Yska; J Visser; D K Meijer
Journal:  Eur J Clin Pharmacol       Date:  1985       Impact factor: 2.953

Review 5.  Rectal drug administration: clinical pharmacokinetic considerations.

Authors:  A G de Boer; F Moolenaar; L G de Leede; D D Breimer
Journal:  Clin Pharmacokinet       Date:  1982 Jul-Aug       Impact factor: 6.447

Review 6.  Clinical pharmacokinetics and pharmacodynamics of opioid analgesics in infants and children.

Authors:  K T Olkkola; K Hamunen; E L Maunuksela
Journal:  Clin Pharmacokinet       Date:  1995-05       Impact factor: 6.447

7.  Preliminary study on the absorption profile after rectal and oral administration of methadone in human volunteers.

Authors:  F Moolenaar; G Fiets; J Visser; D K Meijer
Journal:  Pharm Weekbl Sci       Date:  1984-12-14

Review 8.  Preparing children for the operating room: psychological issues.

Authors:  T McGraw
Journal:  Can J Anaesth       Date:  1994-11       Impact factor: 5.063

Review 9.  Clinical pharmacokinetics in infants and children. A reappraisal.

Authors:  G L Kearns; M D Reed
Journal:  Clin Pharmacokinet       Date:  1989       Impact factor: 6.447

10.  The systemic availability of meptazinol in man after oral and rectal doses.

Authors:  G R Murray; O Petitjean; R A Franklin; D F Graham; J H Trouvin; C Jacquot
Journal:  Eur J Clin Pharmacol       Date:  1989       Impact factor: 2.953

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