[Dynamics of changes in the concentration of estradiol receptors in the cytosol of rat female hypothalamus during postnatal development].

Estradiol receptors content in the hypothalamus of female rats during the postnatal development (the 7th, 14th, 21st, 28th, 35th, and 42nd days) was studied. The greatest values of the binding capacity were revealed in the hypothalamus of 7- and 14-day female rats; thses values decreased gradually till sexual maturation. The number of estradiol receptors increased after the vagina opening in rats. Estradiol receptors possessed high sterospecificity and high degree of affinity to the receptive hormone.