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Literature DB >> 7246545

A new genetic model proposing that the Se gene is a structural gene closely linked to the H gene.

Abstract

The Se gene is classically considered as a regulatory gene controlling the expression of the structural gene H in external secretions. Under this hypothesis, Bombay (h/h) individuals should not be able to express the Se gene. Statistical analysis of the 44 published Bombay pedigrees suggests on the contrary that there is no suppression of Se in Bombay individuals, and that both Se and H loci can be fully expressed at the phenotypic level. Based on a lod score of 12.9 at 1% recombination units and the existence of two different acceptors for the biosynthesis of the H antigen, a new genetic model is proposed in which H and Se would be two closely linked structural genes coding for two different 2-alpha-L-fucosyltransferases.

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Year: 1981 PMID： 7246545 PMCID： PMC1685044

Source DB: PubMed Journal: Am J Hum Genet ISSN： 0002-9297 Impact factor: 11.025

43 in total

1. A family of "Bombay" blood type with suppression of blood group substance A1.

Authors: C H AUST; N D HOCKER; Z G KELLER; J L ARBOGAST
Journal: Am J Clin Pathol Date: 1962-06 Impact factor: 2.493

2. Eleven cases of "Bombay" phenotype in six families: suppression of ABO antigen demonstrated in two families.

Authors: S A HAKIM; G N VYAS; L D SANGHVI; H M BHATIA
Journal: Transfusion Date: 1961 Jul-Aug Impact factor: 3.157

3. Ah, an incomplete suppression of A resembling Oh.

Authors: P LEVINE; M UHLIR; J WHITE
Journal: Vox Sang Date: 1961-09 Impact factor: 2.144

4. A "new" blood group character related to the ABO system.

Authors: Y M BHENDE; C K DESHPANDE; H M BHATIA; R SANGER; R R RACE; W T J MORGAN; W M WATKINS
Journal: Lancet Date: 1952-05-03 Impact factor: 79.321

5. A case of Oh (Bombay) blood found in a Thai-Muslim patient.

Authors: S Sringarm; B Sombatpanich; D Chandanayingyong
Journal: Vox Sang Date: 1977-12 Impact factor: 2.144

6. Estimation of the recombination fraction in human pedigrees: efficient computation of the likelihood for human linkage studies.

Authors: J Ott
Journal: Am J Hum Genet Date: 1974-09 Impact factor: 11.025

7. Alpha-L-fucosyltransferases in human serum from donors of different ABO, secretor and Lewis blood-group phenotypes.

Authors: H Schenkel-Brunner; M A Chester; W M Watkins
Journal: Eur J Biochem Date: 1972-10

8. Another example of Lewis negative Bombay bloods.

Authors: H M Pretty; V Taliano; D Fiset; G Baribeau; R Guévin
Journal: Vox Sang Date: 1969-03 Impact factor: 2.144

9. A study of the antibodies of the H"O"I-B complex with special reference to their occurrence and notation.

Authors: D Voak; T W Lodge; J Hopkins; C C Bowley
Journal: Vox Sang Date: 1968 Impact factor: 2.144

10. Activity of 2-alpha-L-fucosyltransferase in human sera and red cell membranes. A study of common ABH blood donors, rare 'Bombay' and 'Parabombay' individuals.

Authors: C Mulet; J P Cartron; J Badet; C Salmon
Journal: FEBS Lett Date: 1977-12-01 Impact factor: 4.124

30 in total

1. Tissue-specific expression of Le(Y) antigen in high endothelial venules of human lymphoid tissues.

Authors: A Tanegashima; I Ushiyama; K Nishi; H Yamamoto; T Fukunaga
Journal: Glycoconj J Date: 1999-12 Impact factor: 2.916

2. Molecular cloning, sequence, and expression of a human GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase cDNA that can form the H blood group antigen.

Authors: R D Larsen; L K Ernst; R P Nair; J B Lowe
Journal: Proc Natl Acad Sci U S A Date: 1990-09 Impact factor: 11.205

3. ABO blood type A is associated with increased risk of ARDS in whites following both major trauma and severe sepsis.

Authors: John P Reilly; Nuala J Meyer; Michael G S Shashaty; Rui Feng; Paul N Lanken; Robert Gallop; Sandra Kaplan; Maximilian Herlim; Nathaniel L Oz; Isabel Hiciano; Ana Campbell; Daniel N Holena; Muredach P Reilly; Jason D Christie
Journal: Chest Date: 2014-04 Impact factor: 9.410

4. Blood group antigen expression is involved in C. albicans interaction with buccal epithelial cells.

Authors: Arun V Everest-Dass; Daniel Kolarich; Dana Pascovici; Nicolle H Packer
Journal: Glycoconj J Date: 2016-09-17 Impact factor: 2.916

5. Ethnic differences in the expression of blood group antigens in the salivary gland secretory cells from German and Japanese non-secretor individuals.

Authors: A Tanegashima; K Nishi; T Fukunaga; S Rand; B Brinkmann
Journal: Glycoconj J Date: 1996-08 Impact factor: 2.916

6. The presence of at least two different H-blood-group-related beta-D-gal alpha-2-L-fucosyltransferases in human serum and the genetics of blood group H substances.

Authors: J Le Pendu; J P Cartron; R U Lemieux; R Oriol
Journal: Am J Hum Genet Date: 1985-07 Impact factor: 11.025

Review 7. Blood group antigens: molecules seeking a function?

Authors: P Greenwell
Journal: Glycoconj J Date: 1997-02 Impact factor: 2.916

8. Histochemical demonstration of O-glycosidically linked, type 3 based ABH antigens in human pancreas using lectin staining and glycosidase digestion procedures.

Authors: N Ito; K Nishi; M Nakajima; Y Okamura; T Hirota
Journal: Histochemistry Date: 1989

9. H-deficient blood groups of Reunion island. II. Differences between Indians (Bombay Phenotype) and whites (Reunion phenotype).

Authors: J Le Pendu; G Gerard; D Vitrac; G Juszczak; G Liberge; P Rouger; C Salmon; F Lambert; A M Dalix; R Oriol
Journal: Am J Hum Genet Date: 1983-05 Impact factor: 11.025

10. Insights into the expression of ABH and Lewis antigens through human bone marrow transplantation.

Authors: R Oriol; J Le Pendu; R S Sparkes; M C Sparkes; M Crist; R P Gale; P I Terasaki; M Bernoco
Journal: Am J Hum Genet Date: 1981-07 Impact factor: 11.025