Changes in the binocular fixation patterns and the visually evoked potential in the treatment of esotropia with amblyopia.

Using the binocular fixation pattern (BFP) and the visually evoked potential (VEP), thirteen amblyopic patients with comitant, non-accommodative esotropia with an angle range up to 30 delta were studied before and during occlusion therapy. A graded BFP with a stronger preferred fixation could be used to diagnose amblyopia. The BFP, however, showed no significant change with therapy despite improvement in acuity. In contrast, the VEP amplitudes, initially reduced in amblyopia, increased significantly as the vision responded to patching. The VEP was useful in diagnosing strabismic amblyopia and giving a predictive range of acuities.