Literature DB >> 7241956

Diuretic treatment and serum lipoproteins: effects of tienilic acid and indapamide.

P Weidmann, A Meier, R Mordasini, W Riesen, C Bachmann, E Peheim.   

Abstract

Treatment with the commonly used diuretic, chlorthalidone, has previously been found to increase the serum low-density-lipoprotein cholesterol (LDL-C) fraction. Therefore, the effects of two new agents, tienilic acid (a combined diuretic-uricosuric) and indapamide on serum lipid and lipoprotein levels were assessed. Six weeks of treatment with tienilic acid, 250 mg/day, markedly decreased serum uric acid and significantly increased LDL-C and triglycerides in 16 men. In contrast, indapamide 2.5 mg/day, had no apparent influence on serum lipids or lipoproteins in 18 men.

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Year:  1981        PMID： 7241956     DOI： 10.1007/bf01525002

Source DB:  PubMed          Journal:  Klin Wochenschr        ISSN： 0023-2173


  13 in total

1.  Selective deficiency of hepatic triglyceride lipase in uremic patients.

Authors:  R Mordasini; F Frey; W Flury; G Klose; H Greten
Journal:  N Engl J Med       Date:  1977-12-22       Impact factor: 91.245

2.  Immunochemical quantitation of antigens by single radial immunodiffusion.

Authors:  G Mancini; A O Carbonara; J F Heremans
Journal:  Immunochemistry       Date:  1965-09

3.  Effects of diuretics on plasma lipoproteins in healthy men.

Authors:  C Joos; H Kewitz; D Reinhold-Kourniati
Journal:  Eur J Clin Pharmacol       Date:  1980-04       Impact factor: 2.953

4.  Ticrynafen: a new thiazid-like but uricosuric antihypertensive diuretic.

Authors:  E D Frohlich
Journal:  N Engl J Med       Date:  1979-12-20       Impact factor: 91.245

5.  Increased ratio between serum beta- and alpha-lipoproteins during diuretic therapy: an adverse effect?

Authors:  Z Glück; G Baumgartner; P Weidmann; E Peheim; C Bachmann; R Mordasini; J Flammer; G Keusch
Journal:  Clin Sci Mol Med Suppl       Date:  1978-12

6.  HDL cholesterol and other lipids in coronary heart disease. The cooperative lipoprotein phenotyping study.

Authors:  W P Castelli; J T Doyle; T Gordon; C G Hames; M C Hjortland; S B Hulley; A Kagan; W J Zukel
Journal:  Circulation       Date:  1977-05       Impact factor: 29.690

7.  Interrelations among blood pressure, blood volume, plasma renin activity and urinary catecholamines in benign essential hypertension.

Authors:  P Weidmann; D Hirsch; C Beretta-Piccoli; F C Reubi; W H Ziegler
Journal:  Am J Med       Date:  1977-02       Impact factor: 4.965

8.  Increased serum low-density lipoprotein cholesterol in men treated short-term with the diuretic chlorthalidone.

Authors:  Z Glück; P Weidmann; R Mordasini; C Bachmann; W Riesen; E Peheim; G Keusch; A Meier
Journal:  Metabolism       Date:  1980-03       Impact factor: 8.694

9.  Elevation of serum lipid levels during diuretic therapy of hypertension.

Authors:  R P Ames; P Hill
Journal:  Am J Med       Date:  1976-11       Impact factor: 4.965

10.  Ticrynafen: a novel uricosuric antihypertensive natriuretic agent.

Authors:  J G de Carvalho; F G Dunn; S G Chrysant; E D Frohlich
Journal:  Arch Intern Med       Date:  1978-01
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  9 in total

1.  Effects of diuretics alone or in combination with beta-adrenoceptor blockers on serum lipoproteins.

Authors:  P Weidmann; H Schiffl; K Boehringer; A Meier; R Mordasini; W Riesen
Journal:  Br J Clin Pharmacol       Date:  1982       Impact factor: 4.335

Review 2.  The effects of diuretics and adrenergic-blocking agents on plasma lipids.

Authors:  J J Rohlfing; J D Brunzell
Journal:  West J Med       Date:  1986-08

Review 3.  Diuretics. Clinical pharmacology and therapeutic use (Part II).

Authors:  A Lant
Journal:  Drugs       Date:  1985-02       Impact factor: 9.546

4.  Effect of indapamide on the baroreceptor reflex in essential hypertension.

Authors:  R Carretta; B Fabris; L Tonutti; G Bellini; G Battilana; A Bianchetti; L Campanacci
Journal:  Eur J Clin Pharmacol       Date:  1983       Impact factor: 2.953

Review 5.  Serum lipoproteins during treatment with antihypertensive drugs.

Authors:  P Weidmann; C Ferrier; H Saxenhofer; D E Uehlinger; B N Trost
Journal:  Drugs       Date:  1988       Impact factor: 9.546

Review 6.  [Alterations of fat metabolism in renal disease - pathogenetic mechanisms (author's transl)].

Authors:  W H Hörl; M Hörl; A Heidland
Journal:  Klin Wochenschr       Date:  1982-04-01

Review 7.  The effects of antihypertensive drugs on serum lipids and lipoproteins, I. Diuretics.

Authors:  R P Ames
Journal:  Drugs       Date:  1986-09       Impact factor: 9.546

8.  Serum lipoproteins in patients with mild renal disease treated with the diuretic muzolimine.

Authors:  H Schiffl; P Weidmann; R Mordasini; K Boehringer; W Riesen; C Bachmann
Journal:  Klin Wochenschr       Date:  1982-12-01

9.  Indapamide. A review of its pharmacodynamic properties and therapeutic efficacy in hypertension.

Authors:  M Chaffman; R C Heel; R N Brogden; T M Speight; G S Avery
Journal:  Drugs       Date:  1984-09       Impact factor: 9.546
  9 in total

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