Literature DB >> 7237421

Action spectra for ultraviolet light-induced transformation of human cells to anchorage-independent growth.

B M Sutherland, N C Delihas, R P Oliver, J C Sutherland.   

Abstract

We have determined action spectra for transformation of human embryonic skin and muscle fibroblasts to anchorage-independent growth. Tests under our experimental conditions indicate that reciprocity holds for photon rate and exposure time and that all the dose-effect curves in the wavelength range of 248 to 297 nm are smaller. These data can be used to construct action spectra with a maximum at about 265 nm, which do not implicate moieties other than nucleic acids as absorbers in the transformation process.

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Year:  1981        PMID： 7237421

Source DB:  PubMed          Journal:  Cancer Res        ISSN： 0008-5472            Impact factor:   12.701


  5 in total

1.  Animal model for ultraviolet radiation-induced melanoma: platyfish-swordtail hybrid.

Authors:  R B Setlow; A D Woodhead; E Grist
Journal:  Proc Natl Acad Sci U S A       Date:  1989-11       Impact factor: 11.205

Review 2.  Investigating the biochemical impact of DNA damage with structure-based probes: abasic sites, photodimers, alkylation adducts, and oxidative lesions.

Authors:  Heidi A Dahlmann; V G Vaidyanathan; Shana J Sturla
Journal:  Biochemistry       Date:  2009-10-13       Impact factor: 3.162

3.  Different rates of ultraviolet-induced DNA damage in the epidermis and dermis of a platyfish model for carcinogenesis.

Authors:  F E Ahmed
Journal:  Radiat Environ Biophys       Date:  1993       Impact factor: 1.925

4.  Frequency of UV-induced neoplastic transformation of diploid human fibroblasts is higher in xeroderma pigmentosum cells than in normal cells.

Authors:  V M Maher; L A Rowan; K C Silinskas; S A Kateley; J J McCormick
Journal:  Proc Natl Acad Sci U S A       Date:  1982-04       Impact factor: 11.205

5.  Wavelength dependence of pyrimidine dimer formation in DNA of human skin irradiated in situ with ultraviolet light.

Authors:  S E Freeman; H Hacham; R W Gange; D J Maytum; J C Sutherland; B M Sutherland
Journal:  Proc Natl Acad Sci U S A       Date:  1989-07       Impact factor: 11.205
  5 in total

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