Literature DB >> 7237138

Ca2+-accumulation in experimental spinal cord trauma.

R D Happel, K P Smith, N L Banik, J M Powers, E L Hogan, J D Balentine.   

Abstract

Quantitative measurements of the time course of calcium levels in experimental spinal cord trauma have been made. The injury was produced in rats by dropping a 10 g weight from 30 cm upon exposed dura-invested spinal cord. Lumbar sections of traumatized spinal cord and internal controls from remote cervical cord were excised and analyzed for calcium using atomic absorption spectroscopy. Total calcium levels in the lesioned cord were significantly elevated over control values within 45 min post-trauma (P less than 0.005), with maximal increase at 8 h. The increased levels of calcium in the lesion tissue confirm the previous morphologic finding of calcium deposits within axons in the lesion.

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Year:  1981        PMID： 7237138     DOI： 10.1016/0006-8993(81)90976-8

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  24 in total

1.  Effects of dantrolene on apoptosis and immunohistochemical expression of NeuN in the spinal cord after traumatic injury in rats.

Authors:  Bruno Benetti Junta Torres; Fátima Maria Caetano Caldeira; Mardelene Geísa Gomes; Rogéria Serakides; Aline de Marco Viott; Angélica Cavalheiro Bertagnolli; Fabíola Bono Fukushima; Karen Maciel de Oliveira; Marcus Vinícius Gomes; Eliane Gonçalves de Melo
Journal:  Int J Exp Pathol       Date:  2010-10-05       Impact factor: 1.925

2.  Sustained calpain inhibition improves locomotor function and tissue sparing following contusive spinal cord injury.

Authors:  Chen-Guang Yu; James W Geddes
Journal:  Neurochem Res       Date:  2007-05-03       Impact factor: 3.996

3.  Role of calpain in spinal cord injury: increased calpain immunoreactivity in rat spinal cord after impact trauma.

Authors:  Z Li; E L Hogan; N L Banik
Journal:  Neurochem Res       Date:  1996-04       Impact factor: 3.996

4.  Localized and transient elevations of intracellular Ca2+ induce the dedifferentiation of axonal segments into growth cones.

Authors:  N E Ziv; M E Spira
Journal:  J Neurosci       Date:  1997-05-15       Impact factor: 6.167

5.  Low dose estrogen prevents neuronal degeneration and microglial reactivity in an acute model of spinal cord injury: effect of dosing, route of administration, and therapy delay.

Authors:  Supriti Samantaray; Joshua A Smith; Arabinda Das; Denise D Matzelle; Abhay K Varma; Swapan K Ray; Naren L Banik
Journal:  Neurochem Res       Date:  2011-05-25       Impact factor: 3.996

6.  The sequence of ultrastructural changes in cultured neurons after dendrite transection.

Authors:  D G Emery; J H Lucas; G W Gross
Journal:  Exp Brain Res       Date:  1987       Impact factor: 1.972

7.  Pyruvate dehydrogenase complex is inhibited in calcium-loaded cerebrocortical mitochondria.

Authors:  J C Lai; J C DiLorenzo; K F Sheu
Journal:  Neurochem Res       Date:  1988-11       Impact factor: 3.996

8.  IP3R-mediated intra-axonal Ca2+ release contributes to secondary axonal degeneration following contusive spinal cord injury.

Authors:  Ben C Orem; Arezoo Rajaee; David P Stirling
Journal:  Neurobiol Dis       Date:  2020-10-01       Impact factor: 5.996

9.  The effect of duration of compression on lipid peroxidation after experimental spinal cord injury.

Authors:  M Y Kaynar; M Hanci; A Kafadar; K Gümüştaş; A Belce; N Ciplak
Journal:  Neurosurg Rev       Date:  1998       Impact factor: 3.042

10.  Regional calcium levels in rat and mouse brain: automated fluorimetric assay and effects of centrally acting drugs.

Authors:  J Korf; F H Zoethout; F Postema
Journal:  Psychopharmacology (Berl)       Date:  1983       Impact factor: 4.530
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