Literature DB >> 7236250

Is regulation of proteolysis associated with redox-state changes in rat skeletal muscle?

M E Tischler.   

Abstract

In isolated rat diaphragms, only those substrates that increased the tissue NADH/NAD+ ratio lowered the rate of proteolysis. However, direct inhibition of proteinase activity by leupeptin promoted oxidation of the NAD couple of the muscles. These results suggest that changes in muscle reduction-oxidation state may be important in the regulation of proteolysis.

Entities:  

Mesh：

Substances：

Year:  1980        PMID： 7236250      PMCID： PMC1162426          DOI： 10.1042/bj1920963

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  15 in total

1.  Glucogenic substrate levels in fasting man.

Authors:  T T Aoki; C J Toews; A A Rossini; N B Ruderman; G F Cahill
Journal:  Adv Enzyme Regul       Date:  1975

2.  Effects of insulin, glucose, and amino acids on protein turnover in rat diaphragm.

Authors:  R M Fulks; J B Li; A L Goldberg
Journal:  J Biol Chem       Date:  1975-01-10       Impact factor: 5.157

Review 3.  The redox state and regulation of amino acid metabolism in man.

Authors:  T T Aoki; R J Finley; G F Cahill
Journal:  Biochem Soc Symp       Date:  1978

Review 4.  Intracellular protein degradation in mammalian and bacterial cells.

Authors:  A L Goldberg; J F Dice
Journal:  Annu Rev Biochem       Date:  1974       Impact factor: 23.643

5.  Oxidation of leucine by rat skeletal muscle.

Authors:  R Odessey; A L Goldberg
Journal:  Am J Physiol       Date:  1972-12

6.  Effect of isoproterenol on amino acid levels and protein turnover in skeletal muscle.

Authors:  J B Li; L S Jefferson
Journal:  Am J Physiol       Date:  1977-02

7.  Leupeptin, a protease inhibitor, decreases protein degradation in normal and diseased muscles.

Authors:  P Libby; A L Goldberg
Journal:  Science       Date:  1978-02-03       Impact factor: 47.728

8.  Effect of glucocorticoid administration on the rate of muscle protein breakdown in vivo in rats, as measured by urinary excretion of N tau-methylhistidine.

Authors:  F M Tomas; H N Munro; V R Young
Journal:  Biochem J       Date:  1979-01-15       Impact factor: 3.857

9.  The redox state of free nicotinamide-adenine dinucleotide in the cytoplasm and mitochondria of rat liver.

Authors:  D H Williamson; P Lund; H A Krebs
Journal:  Biochem J       Date:  1967-05       Impact factor: 3.857

10.  Studies concerning the specificity of the effect of leucine on the turnover of proteins in muscles of control and diabetic rats.

Authors:  M G Buse; D A Weigand
Journal:  Biochim Biophys Acta       Date:  1977-03-02
View more
  9 in total

Review 1.  Regulation of protein turnover in skeletal and cardiac muscle.

Authors:  P H Sugden; S J Fuller
Journal:  Biochem J       Date:  1991-01-01       Impact factor: 3.857

2.  The rate of protein degradation in isolated skeletal muscle does not correlate with reduction-oxidation status.

Authors:  J M Fagan; A L Goldberg
Journal:  Biochem J       Date:  1985-05-01       Impact factor: 3.857

3.  Effects of acute ethanol administration on rat liver 5-aminolaevulinate synthase activity.

Authors:  A A Badawy; C J Morgan; N R Davis
Journal:  Biochem J       Date:  1989-09-01       Impact factor: 3.857

4.  Glutamine supplementation in sick children: is it beneficial?

Authors:  Elise Mok; Régis Hankard
Journal:  J Nutr Metab       Date:  2011-11-14

5.  Effect of starvation and refeeding on amino acid uptake by mammary gland of the lactating rat. Role of ketone bodies.

Authors:  J R Viña; I R Puertes; J B Montoro; J Viña
Journal:  Biochem J       Date:  1983-11-15       Impact factor: 3.857

6.  Specificity of the effects of leucine and its metabolites on protein degradation in skeletal muscle.

Authors:  W E Mitch; A S Clark
Journal:  Biochem J       Date:  1984-09-15       Impact factor: 3.857

7.  Relationship between a long-term treatment of 2-mercaptoethanol and protein metabolism in the ageing rat.

Authors:  V Albrecht; L Pénzes; K J Petzke; K Hoppe
Journal:  J Comp Physiol B       Date:  1992       Impact factor: 2.200

8.  Effect of insulin and lack of effect of workload and hypoxia on protein degradation in the perfused working rat heart.

Authors:  D M Smith; P H Sugden
Journal:  Biochem J       Date:  1983-01-15       Impact factor: 3.857

9.  Muscle protein turnover and glucose uptake in acutely uremic rats. Effects of insulin and the duration of renal insufficiency.

Authors:  A S Clark; W E Mitch
Journal:  J Clin Invest       Date:  1983-09       Impact factor: 14.808
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.