Literature DB >> 7236108

S-antigen uveitis in primates. A new model for human disease.

R B Nussenblatt, T Kuwabara, F M de Monasterio, W B Wacker.   

Abstract

Uveitis was induced rhesus monkeys immunized with purified retinal S-antigen. Focal retinal and subretinal infiltration, in addition to periphlebitic changes, were observed histologically. Immunized monkeys had similar cell-mediated in vitro immune responses to the S-antigen as do humans with posterior uveitis. Circulating immune complexes at the time of disease could not be detected. This primate model supports the notion that the S-antigen may play a role in human uveitis.

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Year:  1981        PMID： 7236108     DOI： 10.1001/archopht.1981.03930011090021

Source DB:  PubMed          Journal:  Arch Ophthalmol        ISSN： 0003-9950


  36 in total

Review 1.  Birdshot retinochoroidopathy.

Authors:  A T Gasch; J A Smith; S M Whitcup
Journal:  Br J Ophthalmol       Date:  1999-02       Impact factor: 4.638

2.  Identification of Th2-type suppressor T cells among in vivo expanded ocular T cells in mice with experimental autoimmune uveoretinitis.

Authors:  H Keino; M Takeuchi; J Suzuki; S Kojo; J Sakai; K Nishioka; T Sumida; M Usui
Journal:  Clin Exp Immunol       Date:  2001-04       Impact factor: 4.330

3.  Isolation and structure of an arrestin gene from Drosophila.

Authors:  D P Smith; B H Shieh; C S Zuker
Journal:  Proc Natl Acad Sci U S A       Date:  1990-02       Impact factor: 11.205

Review 4.  Endogenous posterior uveitis.

Authors:  J V Forrester
Journal:  Br J Ophthalmol       Date:  1990-10       Impact factor: 4.638

5.  Circulating immune complexes may play a regulatory and pathogenic role in experimental autoimmune uveoretinitis.

Authors:  E Kasp; M R Stanford; E Brown; A G Coombes; D C Dumonde
Journal:  Clin Exp Immunol       Date:  1992-05       Impact factor: 4.330

6.  Gene expression profiling in autoimmune noninfectious uveitis disease.

Authors:  Zhuqing Li; Baoying Liu; Arvydas Maminishkis; Sankaranarayana P Mahesh; Steven Yeh; Julie Lew; Wee Kiak Lim; H Nida Sen; Grace Clarke; Ronald Buggage; Sheldon S Miller; Robert B Nussenblatt
Journal:  J Immunol       Date:  2008-10-01       Impact factor: 5.422

Review 7.  Immunoregulation of uveitis.

Authors:  R B Nussenblatt
Journal:  Int Ophthalmol       Date:  1990-01       Impact factor: 2.031

8.  Rhodopsin-induced experimental autoimmune uveoretinitis in monkeys.

Authors:  J J Schalken; H J Winkens; A H Van Vugt; W J De Grip; R M Broekhuyse
Journal:  Br J Ophthalmol       Date:  1989-03       Impact factor: 4.638

9.  Retinal S-antigen Th1 cell epitope mapping in patients with Behcet's disease.

Authors:  Changlin Zhao; Peizeng Yang; Hao He; Xiaomin Lin; Liping Du; Hongyan Zhou; Aize Kijlstra
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2008-10-29       Impact factor: 3.117

Review 10.  Biologic agents in experimental autoimmune uveitis.

Authors:  Gian Paolo Giuliari; Ama Sadaka; David M Hinkle
Journal:  Int Ophthalmol       Date:  2013-03-14       Impact factor: 2.031
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