Literature DB >> 7236074

CSF perfusion to treat intraventricular penicillin toxicity.

J T Callaghan, J I Ausman, R Clubb.   

Abstract

A shunt infection and meningitis developed in a patient receiving methotrexate intravenously for CNS leukemia. Convulsions and respiratory failure followed the intraventricular administration of 300,000 units of penicillin G potassium. Perfusion with 900 mL of Ringer's lactate removed an amount of penicillin equal to that injected intraventricularly plus some from systemic treatment.

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Year:  1981        PMID： 7236074     DOI： 10.1001/archneur.1981.00510060092022

Source DB:  PubMed          Journal:  Arch Neurol        ISSN： 0003-9942


  2 in total

Review 1.  Transient focal leukoencephalopathy following intraventricular methotrexate and cytarabine. A complication of the Ommaya reservoir: case report and review of the literature.

Authors:  V Colamaria; R Caraballo; C Borgna-Pignatti; P Marradi; R Balter; C Mazza; C Procacci; B Dalla Bernardina
Journal:  Childs Nerv Syst       Date:  1990-06       Impact factor: 1.475

2.  Errors by paediatric residents in calculating drug doses.

Authors:  C Rowe; T Koren; G Koren
Journal:  Arch Dis Child       Date:  1998-07       Impact factor: 3.791
  2 in total

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