Literature DB >> 7235685

Comparative nephrotoxicities of dibekacin, amikacin, and gentamicin in a rat model.

L I Rankin, F C Luft, M N Yum, L L Isaacs.   

Abstract

The nephrotoxicity of dibekacin was compared with those of gentamicin and amikacin in a rat model. The doses used were 3, 10, and 30 times the suggested human therapeutic dose on a weight basis. Indices of glomerular and tubular function failed to clearly differentiate the drugs. Dibekacin and gentamicin produced equally severe injury to the renal tissue. Slightly less damage occurred with amikacin.

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Year:  1980        PMID： 7235685      PMCID： PMC353003          DOI： 10.1128/AAC.18.6.983

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  6 in total

1.  AUTOMATED AND MANUAL DIRECT METHODS FOR THE DETERMINATION OF BLOOD UREA.

Authors:  W H MARSH; B FINGERHUT; H MILLER
Journal:  Clin Chem       Date:  1965-06       Impact factor: 8.327

2.  Enzymuria in gentamicin-induced kidney damage.

Authors:  V Patel; F C Luft; M N Yum; B Patel; W Zeman; S A Kleit
Journal:  Antimicrob Agents Chemother       Date:  1975-03       Impact factor: 5.191

3.  A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding.

Authors:  M M Bradford
Journal:  Anal Biochem       Date:  1976-05-07       Impact factor: 3.365

4.  3',4'-dideoxy-kanamycin B active against kanamycin-resistant Escherichia coli and Pseudomonas aeruginosa.

Authors:  H Umezawa; S Umezawa; T Tsuchiya; Y Okazaki
Journal:  J Antibiot (Tokyo)       Date:  1971-07       Impact factor: 2.649

5.  In vitro comparison of kanamycin, kanendomycin, gentamicin, amikacin, sisomicin, and dibekacin against 200 strains of Pseudomonas aeruginosa.

Authors:  A G Paradelis; J Douboyas; G Stathopoulos; A Grigoriadou-Edipides; C Triantaphylidis; J Papapanagiotou
Journal:  Antimicrob Agents Chemother       Date:  1978-09       Impact factor: 5.191

6.  Comparative nephrotoxicity of aminoglycoside antibiotics in rats.

Authors:  F C Luft; R Bloch; R S Sloan; M N Yum; R Costello; D R Maxwell
Journal:  J Infect Dis       Date:  1978-10       Impact factor: 5.226
  6 in total
  2 in total

1.  Evaluation of urinary elimination of N-acetyl-beta-glucosaminidase in healthy volunteers treated with dibekacin or gentamicin.

Authors:  J Camí; J Segura; J E Baños; I Garcia; L Drobnic
Journal:  Antimicrob Agents Chemother       Date:  1982-06       Impact factor: 5.191

Review 2.  Sisomicin, netilmicin and dibekacin. A review of their antibacterial activity and therapeutic use.

Authors:  P Noone
Journal:  Drugs       Date:  1984-06       Impact factor: 9.546
  2 in total

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