Literature DB >> 7233650

Preservation of the ischaemic canine kidney with inosine.

D Rothwell, J Bartley, M James.   

Abstract

Direct intra-renal perfusion of inosine was found to protect the canine kidney from 90 min of warm ischaemia. Significantly lower (P less than 0.01) serum creatinine levels were found 24 and 72 h post-operatively in an inosine treated group (N = 12) when compared to a control group (N = 5). Histological examination of the pre-treated kidneys confirmed the protective effect of inosine.

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Year:  1981        PMID： 7233650     DOI： 10.1007/bf00256680

Source DB:  PubMed          Journal:  Urol Res        ISSN： 0300-5623


  7 in total

1.  Protective effect of inosine on the canine kidney during ischaemia at 37 C.

Authors:  A R Fernando; D M Armstrong; W F Hendry; E P O'Donoghue; J P Ward; L E Watkinson; J E Wickham
Journal:  Transplantation       Date:  1977-06       Impact factor: 4.939

2.  Inosine in preservation of rabbit kidneys for transplantation.

Authors:  M R Buhl; E Kemp; G Kemp
Journal:  Transplant Proc       Date:  1977-09       Impact factor: 1.066

3.  Renal preservation with inosine.

Authors:  Y C Woo; S F Johnson; R B Smith; J J Kaufman; S A Sacks
Journal:  Transplant Proc       Date:  1977-09       Impact factor: 1.066

4.  Mechanisms of drug action on recovery processes of cardiac muscle in myocardial infarction.

Authors:  L F Nikolaeva; N M Cherpachenko; S A Veselova; R I Sokolova
Journal:  Circ Res       Date:  1974-09       Impact factor: 17.367

5.  Canine kidney preservation using a new perfusate.

Authors:  S A Sacks; P H Petritsch; J J Kaufman
Journal:  Lancet       Date:  1973-05-12       Impact factor: 79.321

6.  Enhanced preservation of the ischaemic kidney with inosine.

Authors:  A R Fernando; D M Armstrong; J R Griffiths; W F Hendry; E P O'Donoghue; D Perrett; J P Ward; J E Wickham
Journal:  Lancet       Date:  1976-03-13       Impact factor: 79.321

7.  Inosine: clinical results of ischaemic renal surgery.

Authors:  J E Wickham; A R Fernando; W F Hendry; L E Watkinson; H N Whitfield
Journal:  Br J Urol       Date:  1978-12
  7 in total
  5 in total

1.  Mechanisms whereby exogenous adenine nucleotides improve rabbit renal proximal function during and after anoxia.

Authors:  L J Mandel; T Takano; S P Soltoff; S Murdaugh
Journal:  J Clin Invest       Date:  1988-04       Impact factor: 14.808

2.  Failure of inosine to prevent ischemic damage in the canine and rat kidney models.

Authors:  S E Okiye; H Zincke; G Aydin; A R Zinsmeister
Journal:  Urol Res       Date:  1984

3.  The guanosine-adenosine interaction exists in vivo.

Authors:  Edwin K Jackson; Zaichuan Mi
Journal:  J Pharmacol Exp Ther       Date:  2014-07-07       Impact factor: 4.030

4.  Guanosine regulates adenosine levels in the kidney.

Authors:  Edwin K Jackson; Dongmei Cheng; Zaichuan Mi; Delbert G Gillespie
Journal:  Physiol Rep       Date:  2014-05-28

5.  8-Aminoguanine Induces Diuresis, Natriuresis, and Glucosuria by Inhibiting Purine Nucleoside Phosphorylase and Reduces Potassium Excretion by Inhibiting Rac1.

Authors:  Edwin K Jackson; Zaichuan Mi; Thomas R Kleyman; Dongmei Cheng
Journal:  J Am Heart Assoc       Date:  2018-11-06       Impact factor: 5.501
  5 in total

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