| Literature DB >> 7233445 |
Abstract
LC50-experiments have been conducted using guppies subjected to 72 industrial pollutants. The correlation of the LC50 with several expressions of the hydrophobicity of these chemicals has been studied. Calculated log Poct-values appeared to satisfy more than HPLC retention indices, solubility data or molecular connectivity indices. One QSAR, with log Poct as the only variable, gave good estimations of the toxicity of most of the tested compounds with log Poct less than 6. No LC50 could be determined for solutions of compounds with log Poct greater than 6.Entities:
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Year: 1981 PMID: 7233445 DOI: 10.1016/0300-483x(81)90130-x
Source DB: PubMed Journal: Toxicology ISSN: 0300-483X Impact factor: 4.221