| Literature DB >> 7232477 |
M P Carey, J A Ross, M P Enns.
Abstract
The effects of naloxone hydrochloride on food and water intake and number of wheel revolutions were measured in male rats. The administration of 10 mg/kg naloxone but not 1 mg/kg suppressed the 3-hr food and water intake in nondeprived rats. Naloxone injections (1 mg/kg or 10 mg/kg) were ineffective in altering the number of wheel revolutions in nondeprived or food deprived rats. These results support the interpretation that the suppressive effects of naloxone previously reported with deprived rats are evident in nondeprived rats and are specific to feeding and drinking.Entities:
Mesh：
Substances：
Year: 1981 PMID： 7232477 DOI： 10.1016/0091-3057(81)90318-x
Source DB: PubMed Journal: Pharmacol Biochem Behav ISSN： 0091-3057 Impact factor: 3.533