Save the spleen--an experimental study on the effects of three tissue adhesives on deep wounds of liver and spleen.

Because opinions on the advisability of splenectomy, especially in children, have recently changed considerably, an experiment was set up to study the application of 3 hemostatics in deep injuries to the liver and to the spleen in 29 rabbits and to dogs. Of the 3 substances tested GRF-adhesive and Avitene appeared to give reasonably good results in splenic injuries, but a supplementary suturing procedure or a ligation of the vessels seemed desirable. The effect of GRF-adhesive on liver injuries was satisfactory.