Literature DB >> 7231392

Thymidylate synthetase as target enzyme for the inhibitory activity of 5-substituted 2'-deoxyuridines on mouse leukemia L1210 cell growth.

E De Clercq, J Balzarini, P F Torrence, M P Mertes, C L Schmidt, D Shugar, P J Barr, A S Jones, G Verhelst, R T Walker.   

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Year:  1981        PMID： 7231392

Source DB:  PubMed          Journal:  Mol Pharmacol        ISSN： 0026-895X            Impact factor:   4.436


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  20 in total

Review 1.  Structural modifications of nucleosides in ionic liquids.

Authors:  Vineet Kumar; Virinder S Parmar; Sanjay V Malhotra
Journal:  Biochimie       Date:  2010-02-21       Impact factor: 4.079

2.  Antiviral activities of 5-ethynyl-1-beta-D-ribofuranosylimidazole-4- carboxamide and related compounds.

Authors:  E De Clercq; M Cools; J Balzarini; R Snoeck; G Andrei; M Hosoya; S Shigeta; T Ueda; N Minakawa; A Matsuda
Journal:  Antimicrob Agents Chemother       Date:  1991-04       Impact factor: 5.191

Review 3.  Vaccinia virus inhibitors as a paradigm for the chemotherapy of poxvirus infections.

Authors:  E De Clercq
Journal:  Clin Microbiol Rev       Date:  2001-04       Impact factor: 26.132

4.  Antitumor cell and antimetabolic effects of 5-ethyl-2'-deoxyuridine and 5'-substituted 5-ethyl-2'-deoxyuridine derivatives.

Authors:  J Balzarini; E De Clercq; G Kiefer; K Keppeler; A Buchele
Journal:  Invest New Drugs       Date:  1984       Impact factor: 3.850

5.  Synthesis and biological properties of 2'-deoxy-5-vinyluridine and 2'deoxy-5-vinylcytidine.

Authors:  S G Rahim; M J Duggan; R T Walker; A S Jones; R L Dyer; J Balzarini; E De Clercq
Journal:  Nucleic Acids Res       Date:  1982-09-11       Impact factor: 16.971

6.  Hydantoin derivatives of L- and D-amino acids: synthesis and evaluation of their antiviral and antitumoral activity.

Authors:  Zrinka Rajic; Branka Zorc; Silvana Raic-Malic; Katja Ester; Marijeta Kralj; Kresimir Pavelic; Jan Balzarini; Erik De Clercq; Mladen Mintas
Journal:  Molecules       Date:  2006-11-01       Impact factor: 4.411

7.  Thymidylate synthetase-deficient mouse FM3A mammary carcinoma cell line as a tool for studying the thymidine salvage pathway and the incorporation of thymidine analogues into host cell DNA.

Authors:  J Balzarini; E De Clercq; D Ayusawa; T Seno
Journal:  Biochem J       Date:  1984-01-01       Impact factor: 3.857

8.  2',5'-Bis-O-(tert-butyldimethylsilyl)-3'-spiro-5''-(4''-amino-1'',2''- oxathiole-2'',2'-dioxide)pyrimidine (TSAO) nucleoside analogues: highlyselective inhibitors of human immunodeficiency virus type 1 that are targeted at the viral reverse transcriptase.

Authors:  J Balzarini; M J Pérez-Pérez; A San-Félix; D Schols; C F Perno; A M Vandamme; M J Camarasa; E De Clercq
Journal:  Proc Natl Acad Sci U S A       Date:  1992-05-15       Impact factor: 11.205

9.  Differential antiherpesvirus and antiretrovirus effects of the (S) and (R) enantiomers of acyclic nucleoside phosphonates: potent and selective in vitro and in vivo antiretrovirus activities of (R)-9-(2-phosphonomethoxypropyl)-2,6-diaminopurine.

Authors:  J Balzarini; A Holy; J Jindrich; L Naesens; R Snoeck; D Schols; E De Clercq
Journal:  Antimicrob Agents Chemother       Date:  1993-02       Impact factor: 5.191

10.  Xylotubercidin against herpes simplex virus type 2 in mice.

Authors:  E De Clercq; M J Robins
Journal:  Antimicrob Agents Chemother       Date:  1986-11       Impact factor: 5.191
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