Literature DB >> 7230272

Influence of sex and age on the biological half-life of cadmium in mice.

T Taguchi, S Suzuki.   

Abstract

The influence of age on the whole-body biological half-life of 109Cd was studied in male mice following ip injection. The influence of sex on whole-body and organ retention was ascertained after sc injection. The whole-body biological half-life of 109Cd of the older mice was more than twice that of the younger mice, and that of the female mice was longer than that of the male. In kidneys and salivary glands the biological half-lives of 109Cd of females were also longer than those of males. These differences demonstrate a biological difference between males and females with respect to whole-body half-life of 109Cd. The effects of age and sex on the biological half-life of Cd in mice are assessed quantitatively.

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Year:  1981        PMID: 7230272     DOI: 10.1080/15287398109529975

Source DB:  PubMed          Journal:  J Toxicol Environ Health        ISSN: 0098-4108


  3 in total

1.  Biological half-time and body burden of cadmium in dogs after a long-term oral administration of cadmium.

Authors:  K Matsuno; Y Kodama; K Tsuchiya
Journal:  Biol Trace Elem Res       Date:  1991-05       Impact factor: 3.738

2.  Gestational Cd Exposure in the CD-1 Mouse Induces Sex-Specific Hepatic Insulin Insensitivity, Obesity, and Metabolic Syndrome in Adult Female Offspring.

Authors:  Thomas W Jackson; Garret L Ryherd; Chris M Scheibly; Aubrey L Sasser; T C Guillette; Scott M Belcher
Journal:  Toxicol Sci       Date:  2020-12-01       Impact factor: 4.849

3.  Gestational Cd Exposure in the CD-1 Mouse Sex-Specifically Disrupts Essential Metal Ion Homeostasis.

Authors:  Thomas W Jackson; Oliver Baars; Scott M Belcher
Journal:  Toxicol Sci       Date:  2022-05-26       Impact factor: 4.109

  3 in total

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