Literature DB >> 7230126

Effect of dihydrotestosterone on follicular development, ovulation and reproductive capacity of mice.

T D Nandedkar, S R Munshi.   

Abstract

A single injection of a 5 alpha-dihydrotestosterone (DHT) was administered to cyclic female mice on the day of metoestrus. DHT (1 mg) prolonged the dioestrous stage of the cycle by 24 h and there were 50% fewer large (normal) follicles than in oil-injected controls. Degenerating ova were observed in the oviduct of 70% of the DHT-treated mice and there was a significant reduction in the numbers of females becoming pregnant and bearing normal fetuses.

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Year:  1981        PMID： 7230126     DOI： 10.1530/jrf.0.0620021

Source DB:  PubMed          Journal:  J Reprod Fertil        ISSN： 0022-4251


  3 in total

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Review 2.  The role of steroids in follicular growth.

Authors:  Ann E Drummond
Journal:  Reprod Biol Endocrinol       Date:  2006-04-10       Impact factor: 5.211

3.  Androgen Suppresses In Vivo and In Vitro LH Pulse Secretion and Neural Kiss1 and Tac2 Gene Expression in Female Mice.

Authors:  Lourdes A Esparza; Tomohiro Terasaka; Mark A Lawson; Alexander S Kauffman
Journal:  Endocrinology       Date:  2020-12-01       Impact factor: 4.736
  3 in total

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