Literature DB >> 7228501

Synthesis of dermorphins, a new class of opiate-like peptides.

R de Castiglione, F Faoro, G Perseo, S Piani.   

Abstract

H-Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH2 (dermorphin) and H-Tyr-D-Ala-Phe-Gly-Tyr-Hyp-Ser-NH2 (Hyp6-dermorphin) are two members of a new class of opiate-like peptides present in the amphibian skin. Their syntheses and that of the L-Ala2-analogue of dermorphin have been accomplished by conventional segment condensation in solution.

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Year:  1981        PMID: 7228501     DOI: 10.1111/j.1399-3011.1981.tb01991.x

Source DB:  PubMed          Journal:  Int J Pept Protein Res        ISSN: 0367-8377


  3 in total

1.  A conformational study of the opioid peptide dermorphin by one-dimensional and two-dimensional nuclear magnetic resonance spectroscopy.

Authors:  A Pastore; P A Temussi; S Salvadori; R Tomatis; P Mascagni
Journal:  Biophys J       Date:  1985-08       Impact factor: 4.033

2.  Pharmacological data on dermorphins, a new class of potent opioid peptides from amphibian skin.

Authors:  M Broccardo; V Erspamer; G Falconieri Erspamer; G Improta; G Linari; P Melchiorri; P C Montecucchi
Journal:  Br J Pharmacol       Date:  1981-07       Impact factor: 8.739

3.  The use of tritium-labeled dermorphin for studying the interactions of C-terminal dermorphin fragment Tyr-Pro-Ser-NH2 and its stereoisomer Tyr-D-Pro-Ser-NH2 with opioid receptors.

Authors:  P S Gromovykh; O Yu Sokolov; N V Kost; A A Zozulya; L S Guzevatykh; L A Andreeva; L Yu Alfeeva; K V Shevchenko; V P Shevchenko; I Yu Nagaev; N F Myasoyedov
Journal:  Dokl Biol Sci       Date:  2008 Mar-Apr
  3 in total

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