Literature DB >> 7227458

Peristalsis abolishes the release of methionine-enkephalin from guinea-pig ileum in vitro.

S J Clark, T W Smith.   

Abstract

The release of methionine-enkephalin from superfused guinea-pig ileum has been demonstrated. Methionine-enkephalin, as measured by radioimmunoassay, was shown to be released from tissues maintained at an intraluminal pressure of O cm water (resting conditions). Increased intraluminal pressure (5 cm water) induced peristalsis and abolished the release of methionine-enkephalin. These results provide further evidence that endogenous opioids may be involved in the modulation of contractile activity in the guinea-pig ileum.

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Year:  1981        PMID： 7227458     DOI： 10.1016/0014-2999(81)90175-8

Source DB:  PubMed          Journal:  Eur J Pharmacol        ISSN： 0014-2999            Impact factor:   4.432


  8 in total

1.  Effect of opioid peptides on circular muscle of canine duodenum.

Authors:  A J Bauer; J H Szurszewski
Journal:  J Physiol       Date:  1991-03       Impact factor: 5.182

2.  Reflex peristalsis in the guinea pig isolated ileum is endogenously controlled by kappa opioid receptors.

Authors:  W Kromer
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1990-05       Impact factor: 3.000

3.  Evoked release of methionine enkephalin from tolerant/dependent enteric ganglia: paradoxical dependence on morphine.

Authors:  A R Gintzler; W C Chan; J Glass
Journal:  Proc Natl Acad Sci U S A       Date:  1987-04       Impact factor: 11.205

4.  Meal-stimulated release of methionine-enkephalin into the canine jejunal lumen.

Authors:  S R Money; A Petroianu; A R Gintzler; B M Jaffe
Journal:  J Clin Invest       Date:  1988-03       Impact factor: 14.808

5.  Release of dynorphin, somatostatin and substance P from the vascularly perfused small intestine of the guinea-pig during peristalsis.

Authors:  J Donnerer; P Holzer; F Lembeck
Journal:  Br J Pharmacol       Date:  1984-12       Impact factor: 8.739

6.  Differential effects of SKF 10,047 (N-allyl-normetazocine) on peristalsis and longitudinal muscle contractions of the isolated guinea-pig ileum.

Authors:  W Kromer; N Steigemann; G T Shearman
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1982-12       Impact factor: 3.000

7.  Opiates induce long-term increases in prodynorphin-derived peptide levels in the guinea-pig myenteric plexus.

Authors:  R Schulz; K Metzner; T Dandekar; C Gramsch
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1986-08       Impact factor: 3.000

8.  Nociceptin effect on intestinal motility depends on opioid-receptor like-1 receptors and nitric oxide synthase co-localization.

Authors:  Andrei Sibaev; Jakub Fichna; Dieter Saur; Birol Yuece; Jean-Pierre Timmermans; Martin Storr
Journal:  World J Gastrointest Pharmacol Ther       Date:  2015-08-06
  8 in total

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